Cardiac Hypertrophy

Known as: Heart Hypertrophy, Heart--Hypertrophy 
Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Acute myocardial infarction (MI) due to coronary artery occlusion is accompanied by a pathological remodeling response that… (More)
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Highly Cited
2007
Highly Cited
2007
Growing evidence indicates that microRNAs (miRNAs or miRs) are involved in basic cell functions and oncogenesis. Here we report… (More)
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Highly Cited
2006
Highly Cited
2006
Diverse forms of injury and stress evoke a hypertrophic growth response in adult cardiac myocytes, which is characterized by an… (More)
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Highly Cited
2005
Highly Cited
2005
Although increased external load initially induces cardiac hypertrophy with preserved contractility, sustained overload… (More)
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Highly Cited
2005
Highly Cited
2005
Sustained cardiac pressure overload induces hypertrophy and pathological remodeling, frequently leading to heart failure… (More)
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Highly Cited
2004
Highly Cited
2004
Calcineurin (PP2B) is a calcium/calmodulin-activated, serine-threonine phosphatase that transmits signals to the nucleus through… (More)
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Highly Cited
2002
Highly Cited
2002
The heart responds to stress signals by hypertrophic growth, which is accompanied by activation of the MEF2 transcription factor… (More)
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Highly Cited
1998
Highly Cited
1998
In response to numerous pathologic stimuli, the myocardium undergoes a hypertrophic response characterized by increased… (More)
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Highly Cited
1993
Highly Cited
1993
Increasing evidence suggests that angiotensin II (Ang II) may act as a growth factor for the heart. However, direct effects of… (More)
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Highly Cited
1993
Highly Cited
1993
Hypertrophy is a fundamental adaptive process employed by postmitotic cardiac and skeletal muscle in response to mechanical load… (More)
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