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Carboxyl Group
Known as:
Carboxy
, Carboxyl
The univalent radical -COOH; present in and characteristic of organic acids.
National Institutes of Health
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Broader (1)
chemical group
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Highly Cited
2015
Highly Cited
2015
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi
,
Yue Zhao
,
+7 authors
F. Shao
Nature
2015
Corpus ID: 4407455
Inflammatory caspases (caspase-1, -4, -5 and -11) are critical for innate defences. Caspase-1 is activated by ligands of various…
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Highly Cited
2011
Highly Cited
2011
Crystal Structure of the β2Adrenergic Receptor-Gs protein complex
S. Rasmussen
,
Brian T DeVree
,
+17 authors
B. Kobilka
Nature
2011
Corpus ID: 3452645
G protein-coupled receptors (GPCRs) are responsible for the majority of cellular responses to hormones and neurotransmitters as…
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Highly Cited
2008
Highly Cited
2008
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
M. Lundqvist
,
Johannes Stigler
,
G. Elia
,
I. Lynch
,
T. Cedervall
,
K. Dawson
Proceedings of the National Academy of Sciences…
2008
Corpus ID: 11831421
Nanoparticles in a biological fluid (plasma, or otherwise) associate with a range of biopolymers, especially proteins, organized…
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Highly Cited
2007
Highly Cited
2007
Characteristics of hemicellulose, cellulose and lignin pyrolysis
Haiping Yang
,
R. Yan
,
Hanping Chen
,
D. Lee
,
C. Zheng
2007
Corpus ID: 52101732
Highly Cited
2005
Highly Cited
2005
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
D. Sarbassov
,
D. Guertin
,
Siraj M. Ali
,
D. Sabatini
Science
2005
Corpus ID: 45837814
Deregulation of Akt/protein kinase B (PKB) is implicated in the pathogenesis of cancer and diabetes. Akt/PKB activation requires…
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Highly Cited
2001
Highly Cited
2001
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
J. Hugot
,
M. Chamaillard
,
+17 authors
G. Thomas
Nature
2001
Corpus ID: 4427060
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions…
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Highly Cited
2000
Highly Cited
2000
A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9
M. Donoghue
,
F. Hsieh
,
+9 authors
S. Acton
Circulation Research
2000
Corpus ID: 516628
ACE2, the first known human homologue of angiotensin-converting enzyme (ACE), was identified from 5′ sequencing of a human heart…
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Highly Cited
1998
Highly Cited
1998
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
T. Kitada
,
S. Asakawa
,
+6 authors
N. Shimizu
Nature
1998
Corpus ID: 4432261
Parkinson's disease is a common neurodegenerative disease with complex clinical features. Autosomal recessive juvenile…
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Highly Cited
1991
Highly Cited
1991
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
A. Goate
,
M. Chartier-Harlin
,
+18 authors
J. Hardy
Nature
1991
Corpus ID: 4336069
A LOCUS segregating with familial Alzheimer's disease (AD) has been mapped to chromosome 21 (ref. 1), close to the amyloid…
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Highly Cited
1982
Highly Cited
1982
A simple method for displaying the hydropathic character of a protein.
J. Kyte
,
R. Doolittle
Journal of Molecular Biology
1982
Corpus ID: 6945799
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