Carboxyamidotriazole Orotate

Known as: 1,2,3-Carboxyamido-triazole Orotate, CTO 
The orotate salt form of carboxyamidotriazole (CAI), an orally bioavailable small molecule with potential antiangiogenic and antiproliferative… (More)
National Institutes of Health

Papers overview

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2012
2012
The Bcr/Abl kinase has been targeted for the treatment of chronic myelogenous leukaemia (CML) by imatinib mesylate. While… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVES This study sought to establish a model for grading lesion difficulty in interventional chronic total occlusion (CTO… (More)
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Highly Cited
2011
Highly Cited
2011
AIMS In comparison with non-occlusive lesions, percutaneous coronary intervention (PCI) of chronic total occlusions (CTO… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Data on the health status benefits of percutaneous coronary intervention for coronary chronic total occlusions (CTOs… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES Our purpose was to determine if "Japanese style" technical strategies can be successfully applied in the U.S. practice… (More)
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Highly Cited
2007
Highly Cited
2007
Natural killer (NK) cell-or T cell-mediated cytotoxicity traditionally is measured in 4-16 h (51)Cr-release assays (CRA). A new… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES To demonstrate the safety and feasibility of a new concept for CTO recanalization using a controlled antegrade and… (More)
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Highly Cited
2005
Highly Cited
2005
AIMS Chronic total occlusions (CTOs) are commonly found on diagnostic angiography, and there is some evidence from one study that… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVES The study compared procedural outcomes and long-term survival for patients undergoing percutaneous coronary… (More)
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Review
1992
Review
1992
As a common characteristic of tumor cells, as well as of normal proliferating cells in the G1-phase of cell cycle, one finds… (More)
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