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Carbonic Anhydrase IX

Known as: CAIX Protein, Carbonic Anhydrase 9, Carbonic Anhydrase IX [Chemical/Ingredient] 
A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass… 
National Institutes of Health

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CA9 protein, humanCar9 protein, mouseCar9 protein, rat
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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2016
2016
Evaluation of a Carbonic Anhydrase IX-Targeted Near-Infrared Dye for Fluorescence-Guided Surgery of Hypoxic Tumors.
Proof-of-principle studies in ovarian, lung, and brain cancer patients have shown that fluorescence-guided surgery can enable… 
2014
2014
Carnosine inhibits carbonic anhydrase IX-mediated extracellular acidosis and suppresses growth of HeLa tumor xenografts
BackgroundCarbonic anhydrase IX (CA IX) is a transmembrane enzyme that is present in many types of solid tumors. Expression of CA… 
2014
2014
Increased expression of carbonic anhydrase IX in oral submucous fibrosis and oral squamous cell carcinoma
Abstract Background: Cumulative evidence has demonstrated that carbonic anhydrase IX (CAIX) is upregulated in many types of human… 
2013
2013
Interaction of HIF-1α and Notch3 Is Required for the Expression of Carbonic Anhydrase 9 in Breast Carcinoma Cells.
Expression of carbonic anhydrase 9 (CA9) is associated with poor prognosis and increased tumor aggressiveness and does not always… 
2013
2013
Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast
Ductal carcinoma in situ (DCIS) of the breast is difficult to remove completely during surgery as it is not palpable and can… 
2011
2011
Immunopharmacology and In fl ammation Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX
a Department of Internal Medicine-Oncology, University Hospital Zurich, 8091 Zürich, Switzerland b Department of Physiology… 
2010
2010
A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology
Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor… 
2009
2009
Antibody-specific detection of CAIX in breast and prostate cancers.
Highly Cited
2008
Highly Cited
2008
Regulation of hypoxia-inducible genes by ETS1 transcription factor.
Hypoxia-inducible factor (HIF-1) regulates the expression of genes that facilitate tumor cell survival by making them more… 
2007
2007
Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas.
PURPOSE Hypoxia in the tumor microenvironment triggers a variety of genetic and adaptive responses that regulate tumor growth… 
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