Skip to search formSkip to main contentSkip to account menu

Carbamoyl Phosphate Synthetase 1 Activators [MoA]

Known as: Carbamoyl Phosphate Synthase 1 (CPS1) Activators, Carbamoyl Phosphate Synthetase 1 Activators, Carbamoylphosphate Synthase 1 Activators 
National Institutes of Health

Related topics

Related topics

1 relation
Carglumic acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Efficacy and safety of glucokinase activators for type 2 diabetes mellitus: A systematic review
Glucokinase activators (GKAs) are newly drug class proposed for diabetes treatment. This systematic review aimed to assess the… 
2014
2014
Screening assays to identify artificial glmS ribozyme activators.
Ribsowitches are putative drug targets as they often regulate the expression of essential bacterial genes. This finding… 
2012
2012
Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260.
2011
2011
Generation of N-Ethyl-N-nitrosourea (ENU) Diabetes Models in Mice Demonstrates Genotype-specific Action of Glucokinase Activators*
Background: ENU mutagenesis was used to generate new animal models of diabetes. Results: We identified two novel mutations in… 
2010
2010
Metabolic activation of N-thiazol-2-yl benzamide as glucokinase activators: Impacts of glutathione trapping on covalent binding.
2008
2008
Comparative Docking Assessment of Glucokinase Interactions with its Allosteric Activators
Glucokinase (GK) is expressed in multiple organs and plays a key role in hepatic glucose metabolism and pancreatic insulin… 
2006
2006
Therapeutic and diagnostic uses of tktl1 and inhibitors and activators thereof
Method individual mammal aerobic glucose fermentation metabolic pathway (mam-aGF) the degree of use and the correct process flow… 
1999
1999
Transcriptional activation by artificial recruitment in mammalian cells.
We show that the typical "nonclassical" activator, which comprises a fusion protein bearing a component of the transcriptional… 
1999
1999
Maximization of Selenocysteine tRNA and U6 Small Nuclear RNA Transcriptional Activation Achieved by Flexible Utilization of a Staf Zinc Finger*
Transcriptional activators Staf and Oct-1 play critical roles in the activation of small nuclear RNA (snRNA) and snRNA-type gene… 
1974
1974
Cooperative interactions in the binding of allosteric effectors to phosphoenolpyruvate carboxylase.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)