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Carbamoyl Phosphate Synthetase 1 Activators [MoA]

Known as: Carbamoyl Phosphate Synthase 1 (CPS1) Activators, Carbamoyl Phosphate Synthetase 1 Activators, Carbamoylphosphate Synthase 1 Activators 
National Institutes of Health

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1 relation
Carglumic acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Efficacy and safety of glucokinase activators for type 2 diabetes mellitus: A systematic review
Glucokinase activators (GKAs) are newly drug class proposed for diabetes treatment. This systematic review aimed to assess the… 
2014
2014
Screening assays to identify artificial glmS ribozyme activators.
Ribsowitches are putative drug targets as they often regulate the expression of essential bacterial genes. This finding… 
2011
2011
Generation of N-Ethyl-N-nitrosourea (ENU) Diabetes Models in Mice Demonstrates Genotype-specific Action of Glucokinase Activators*
Background: ENU mutagenesis was used to generate new animal models of diabetes. Results: We identified two novel mutations in… 
2010
2010
Metabolic activation of N-thiazol-2-yl benzamide as glucokinase activators: Impacts of glutathione trapping on covalent binding.
2007
2007
Molecular cloning of proteasome activator PA28-beta subunit of large yellow croaker (Pseudosciana crocea) and its coordinated up-regulation with MHC class I alpha-chain and beta 2-microglobulin in…
Highly Cited
2006
Highly Cited
2006
Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats
Glucokinase (GK) is the rate‐limiting enzyme of hepatic glucose metabolism and acts as a sensor for glucose‐stimulated insulin… 
2006
2006
Therapeutic and diagnostic uses of tktl1 and inhibitors and activators thereof
Method individual mammal aerobic glucose fermentation metabolic pathway (mam-aGF) the degree of use and the correct process flow… 
Review
2005
Review
2005
Amyloid pathology and protein kinase C (PKC): possible therapeutics effects of PKC activators.
Amyloid beta-protein (Abeta) is one of the most studied peptides in human neurodegenerative disorders. Although much has been… 
1999
1999
Transcriptional activation by artificial recruitment in mammalian cells.
We show that the typical "nonclassical" activator, which comprises a fusion protein bearing a component of the transcriptional… 
1999
1999
Maximization of Selenocysteine tRNA and U6 Small Nuclear RNA Transcriptional Activation Achieved by Flexible Utilization of a Staf Zinc Finger*
Transcriptional activators Staf and Oct-1 play critical roles in the activation of small nuclear RNA (snRNA) and snRNA-type gene… 
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