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Calvarial skull defect

Known as: Cranial defect, Skull defect 
A localized defect in the bone of the skull resulting from abnormal embryological development. The defect is covered by normal skin. In some cases… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Cranial reconstruction: 3D biomodel and custom-built implant created using additive manufacturing.
Review
2009
Review
2009
Complications of decompressive craniectomy for traumatic brain injury.
Decompressive craniectomy is widely used to treat intracranial hypertension following traumatic brain injury (TBI). Two… 
Highly Cited
2005
Highly Cited
2005
Growth factor-loaded scaffolds for bone engineering.
Highly Cited
2005
Highly Cited
2005
Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4)
Gene therapy approaches to bone tissue engineering have been widely explored. While localized delivery of plasmid DNA encoding… 
Review
2004
Review
2004
Failure of autologous bone-assisted cranioplasty following decompressive craniectomy in children and adolescents.
OBJECT The authors have routinely performed primary autologous cranioplasty to repair skull defects after decompressive… 
Highly Cited
2002
Highly Cited
2002
BMP4-expressing muscle-derived stem cells differentiate into osteogenic lineage and improve bone healing in immunocompetent mice.
Recent advances in molecular biology have led the way for novel approaches to improve bone healing. The ideal growth factor… 
Highly Cited
2001
Highly Cited
2001
Tissue-Engineered Bone Repair of Sheep Cranial Defects with Autologous Bone Marrow Stromal Cells
Cranial bone defect remains a major challenge to craniofacial surgeons because of limited availability of autologous bone graft… 
Highly Cited
2001
Highly Cited
2001
Effect of Bone Morphogenetic Protein-2-Expressing Muscle-Derived Cells on Healing of Critical-Sized Bone Defects in Mice
Background: Cells that express bone morphogenetic protein-2 (BMP-2) can now be prepared by transduction with adenovirus… 
Review
2000
Review
2000
Properties of calcium phosphate ceramics in relation to their in vivo behavior.
B one replacement has been under investigation for many centuries. The first report on bone replacement comes from the bronze age… 
Highly Cited
1997
Highly Cited
1997
Repairing Holes in the Head: A History of Cranioplasty.
Cranioplasty is almost as ancient as trephination, yet its fascinating history has been neglected. There is strong evidence that… 
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