A. Mikos

Publications689
h-index131
Citations60,367
Highly Influential Citations1,345
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Review: tissue engineering for regeneration of articular cartilage.
Joint pain due to cartilage degeneration is a serious problem, affecting people of all ages. Although many techniques, often surgical, are currently employed to treat this affliction, none have had… Expand
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Electrospinning of polymeric nanofibers for tissue engineering applications: a review.
Interest in electrospinning has recently escalated due to the ability to produce materials with nanoscale properties. Electrospun fibers have been investigated as promising tissue engineering… Expand
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Poly(ethylenimine) and its role in gene delivery.
Since the first published examination of poly(ethylenimine) (PEI) as a gene delivery vehicle, there has been a flurry of research aimed at this polycation and its role in gene therapy. Here we will… Expand
  • 1,051
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Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner
Bone is a complex highly structured mechanically active 3D tissue composed of cellular and matrix elements. The true biological environment of a bone cell is thus derived from a dynamic interaction… Expand
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Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery.
Poly(ethylenimine) (PEI) is one of a number of polycations that has been used successfully to transfer genes into living cells. Although PEI shows promise in the field of gene therapy, to date no… Expand
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  • PDF
Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle.
Poly(ethylenimine) (PEI) samples of various molecular weights and pHs were used to transfect endothelial cells to achieve levels of gene expression for comparison. PEIs with nominal molecular weights… Expand
  • 682
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Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor.
The aim of this study is to investigate the effect of the cell culture conditions of three-dimensional polymer scaffolds seeded with rat marrow stromal cells (MSCs) cultured in different bioreactors… Expand
  • 350
  • 24
Biomimetic materials for tissue engineering.
The development of biomaterials for tissue engineering applications has recently focused on the design of biomimetic materials that are capable of eliciting specific cellular responses and directing… Expand
  • 1,536
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Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration.
The physical and spatial architectural geometries of electrospun scaffolds are important to their application in tissue engineering strategies. In this work, poly(epsilon-caprolactone) microfiber… Expand
  • 786
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Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds.
Culture of seeded osteoblastic cells in three-dimensional osteoconductive scaffolds in vitro is a promising approach to produce an osteoinductive material for repair of bone defects. However, culture… Expand
  • 451
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