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Calcium Channels, Q-Type

Known as: Calcium Channels, Q Type, Q-Type Calcium Channel, Q Type VDCC 
CALCIUM CHANNELS located in the neurons of the brain.
National Institutes of Health

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Papers overview

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Highly Cited
2013
Highly Cited
2013
Quantitative Localization of Cav2.1 (P/Q-Type) Voltage-Dependent Calcium Channels in Purkinje Cells: Somatodendritic Gradient and Distinct Somatic Coclustering with Calcium-Activated Potassium…
P/Q-type voltage-dependent calcium channels play key roles in transmitter release, integration of dendritic signals, generation… 
Review
2012
Review
2012
P/Q‐type calcium channel modulators
P/Q‐type calcium channels are high‐voltage‐gated calcium channels contributing to vesicle release at synaptic terminals. A number… 
Highly Cited
2009
Highly Cited
2009
CaV2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: Implications for calcium channelopathies
Alternative splicing is known to generate multiple functionally distinct calcium channel variants that exhibit distinct spatial… 
Highly Cited
2004
Highly Cited
2004
Calcium-Activated Potassium Channels Are Selectively Coupled to P/Q-Type Calcium Channels in Cerebellar Purkinje Neurons
Cerebellar Purkinje neurons fire spontaneously in the absence of synaptic transmission. P/Q-type voltage-gated calcium channels… 
Highly Cited
2004
Highly Cited
2004
Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes)
Highly Cited
2002
Highly Cited
2002
Cdk5/p35 Regulates Neurotransmitter Release through Phosphorylation and Downregulation of P/Q-Type Voltage-Dependent Calcium Channel Activity
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase with close structural homology to the mitotic Cdks… 
Highly Cited
2002
Highly Cited
2002
P/Q-Type Calcium-Channel Blockade in the Periaqueductal Gray Facilitates Trigeminal Nociception: A Functional Genetic Link for Migraine?
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic… 
Highly Cited
2002
Highly Cited
2002
Roscovitine: a novel regulator of P/Q‐type calcium channels and transmitter release in central neurons
Roscovitine is widely used for inhibition of cdk5, a cyclin‐dependent kinase expressed predominantly in the brain. A novel… 
Highly Cited
1999
Highly Cited
1999
Ca2+/calmodulin binds to and modulates P/Q-type calcium channels
Neurotransmitter release at many central synapses is initiated by an influx of calcium ions through P/Q-type calcium channels… 
Highly Cited
1999
Highly Cited
1999
P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A
Spatial and temporal changes in intracellular calcium concentrations are critical for controlling gene expression in neurons. In… 
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