Calcium Channels, Q-Type

Cerebellar Purkinje neurons fire spontaneously in the absence of synaptic transmission. P/Q-type voltage-gated calcium channels… Expand

Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase with close structural homology to the mitotic Cdks… Expand

Roscovitine is widely used for inhibition of cdk5, a cyclin‐dependent kinase expressed predominantly in the brain. A novel… Expand

The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic… Expand

BACKGROUND The genetic basis of most common forms of human paroxysmal disorders of the central nervous system, such as epilepsy… Expand

Neurotransmitter release at many central synapses is initiated by an influx of calcium ions through P/Q-type calcium channels… Expand

P-type and Q-type calcium channels mediate neurotransmitter release at many synapses in the mammalian nervous system. The α1A… Expand

P-type and Q-type calcium channels mediate neurotransmitter release at many synapses in the mammalian nervous system. The alpha… Expand

Spatial and temporal changes in intracellular calcium concentrations are critical for controlling gene expression in neurons. In… Expand

The recently cloned CB2 cannabinoid receptor subtype was stably transfected into AtT-20 and Chinese hamster ovary cells to… Expand