Calcium Channels, Q-Type

Known as: Calcium Channels, Q Type, Q-Type Calcium Channel, Q Type VDCC 
CALCIUM CHANNELS located in the neurons of the brain.
National Institutes of Health

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Papers overview

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2013
2013
Quantitative localization of Cav2.1 (P/Q-type) voltage-dependent calcium channels in Purkinje cells: somatodendritic gradient and distinct somatic coclustering with calcium-activated potassium…
P/Q-type voltage-dependent calcium channels play key roles in transmitter release, integration of dendritic signals, generation… (More)
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Highly Cited
2004
Highly Cited
2004
Calcium-activated potassium channels are selectively coupled to P/Q-type calcium channels in cerebellar Purkinje neurons.
Cerebellar Purkinje neurons fire spontaneously in the absence of synaptic transmission. P/Q-type voltage-gated calcium channels… (More)
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Highly Cited
2002
Highly Cited
2002
Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase with close structural homology to the mitotic Cdks… (More)
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Highly Cited
2002
Highly Cited
2002
P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine?
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic… (More)
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Highly Cited
2001
Highly Cited
2001
Human epilepsy associated with dysfunction of the brain P/Q-type calcium channel
BACKGROUND The genetic basis of most common forms of human paroxysmal disorders of the central nervous system, such as epilepsy… (More)
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Highly Cited
1999
Highly Cited
1999
Ca2+/calmodulin binds to and modulates P/Q-type calcium channels
Neurotransmitter release at many central synapses is initiated by an influx of calcium ions through P/Q-type calcium channels… (More)
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Highly Cited
1999
Highly Cited
1999
Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels.
P-type and Q-type calcium channels mediate neurotransmitter release at many synapses in the mammalian nervous system. The alpha… (More)
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Highly Cited
1999
Highly Cited
1999
P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A
Spatial and temporal changes in intracellular calcium concentrations are critical for controlling gene expression in neurons. In… (More)
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Highly Cited
1999
Highly Cited
1999
Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the α1A subunit of P/Q type calcium channels
The P/Q type voltage-gated Ca2+ channels are involved in membrane excitability and Ca2+-dependent neurotransmitter release within… (More)
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Highly Cited
1999
Highly Cited
1999
Splicing of α1A subunit gene generates phenotypic variants of P- and Q-type calcium channels
P-type and Q-type calcium channels mediate neurotransmitter release at many synapses in the mammalian nervous system. The α1A… (More)
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