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CYT997
Known as:
Tubulin Inhibitor CYT997
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (3)
Lexibulin
Pyridines
Pyrimidines
Papers overview
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2010
2010
Carboplatin combined with the vascular-disrupting agent CYT997 for recurrent glioblastoma multiforme.
J. Lickliter
,
R. Fida
,
+4 authors
P. Briggs
2010
Corpus ID: 75556949
e13591 Background: The outcome in recurrent glioblastoma multiforme (GBM) remains poor although recent experience with regimens…
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2009
2009
Abstract #LB-211: CYT997: Preclinical studies on the antivascular effects and mode of action of a phase II vascular disrupting agent.
D. Segal
,
P. Gangatirkar
,
+7 authors
E. Fantino
2009
Corpus ID: 74742806
AACR Annual Meeting-- Apr 18-22, 2009; Denver, CO CYT997 is an orally available synthetic small molecule that is currently in…
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2009
2009
Discovery of CYT997, a potent vascular disrupting agent and inhibitor of tubulin polymerization
J. Feutrill
,
P. Bukczynska
,
+9 authors
A. Wilks
2009
Corpus ID: 86221834
2008
2008
Phase I evaluation of CYT997, a novel cytotoxic and vascular-disrupting agent, in patients with advanced cancer
J. Lickliter
,
A. Francesconi
,
+7 authors
P. Vasey
2008
Corpus ID: 74457387
3504 Background: CYT997 binds α-tubulin, inhibits microtubule assembly and demonstrates potent anti-tumour and vascular…
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2007
2007
Phase I study of CYT997, a novel cytotoxic and vascular disrupting agent, given as a 24-hour intravenous infusion to patients with advanced solid tumours
J. Lickliter
,
Gregg D. Smith
,
+4 authors
P. Vasey
2007
Corpus ID: 74499984