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CYP2D6*10 Allele

Known as: CYP2D6J, CYP2D6*10, CYP2D6, P34S 
Human CYP2D6*10 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type… 
National Institutes of Health

Related topics

Related topics

11 relations
22q13.1CYP2D6*36 AlleleCytosine to Thymidine Transition AbnormalityDecreased Biochemical Activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
CYP2D6 Genetic Polymorphisms and Phenotypes in Different Ethnicities of Malaysian Breast Cancer Patients
The cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) is an enzyme that is predominantly involved in the metabolism… 
2016
2016
Frequency of CYP2D6*10 genotypes in Pakistani breast cancer patients taking adjuvant tamoxifen.
OBJECTIVE To investigate the frequency of cytochrome P2D6*10 in breast cancer patients. METHODS This retrospective study was… 
2016
2016
National Prociency Testing Result of CYP2D6*10 Genotyping for Adjuvant Tamoxifen Therapy in China
Tamoxifen has been successfully used for treating breast cancer and preventing cancer recurrence. Cytochrome P450 2D6 (CYP2D6… 
2015
2015
No influence of CYP2D6*10 genotype and phenotype on the pharmacokinetics of nebivolol in healthy Chinese subjects
Nebivolol, a clinically important antihypertensive drug, mainly metabolized by cytochrome P450 (CYP) 2D6, shows wide… 
2014
2014
Statin therapy correlated CYP2D6 gene polymorphism and hyperlipidemia
Abstract Purpose: To investigate the distribution of statin therapy correlated gene polymorphism allele CYP2D6*10 (C188T) in… 
2012
2012
Allelic and genotype frequencies of catechol-O-methyltransferase (Val158Met) and CYP2D6*10 (Pro34Ser) single nucleotide polymorphisms in the Philippines.
A hospital-based cross-sectional study was conducted to determine the allelic and genotype frequencies in the genes encoding for… 
2002
2002
Correlation of tramadol pharmacokinetics and CYP2D6*10 genotype in Malaysian subjects.
1999
1999
A puzzling case of seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration
We present a puzzling case of a 25‐year‐old depressive man suffering from seizures and visual hallucinations during clomipramine… 
1998
1998
Genetic analysis of the CYP2D6 gene in patients with Parkinson's disease.
Highly Cited
1994
Highly Cited
1994
The cytochrome P450 CYP2D6 allelic variant CYP2D6J and related polymorphisms in a European population.
DNA from two subjects showing anomalous CYP2D6 phenotype-genotype relationships was analysed for the presence of new CYP2D6… 
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