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CYP2C9*8 Allele

Known as: CYP2C9, c.449G>A, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*8 Allele, CYP2C9, R150H 
Human CYP2C9*8 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele… Expand
National Institutes of Health

Related topics

Related topics

12 relations
10q24Enhanced Biochemical ActivityGuanosine to Adenosine Transition AbnormalityIron Chelation
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
CYP2C9 Allelic Variants and Frequencies in a Pediatric Sickle Cell Disease Cohort: Implications for NSAIDs Pharmacotherapy
Nonsteroidal anti‐inflammatory drugs (NSAIDs) used to treat pain in patients with sickle cell disease (SCD) are metabolized by… Expand
2011
2011
Population diversity and the performance of warfarin dosing algorithms.
  • G. Suarez-Kurtz
  • British journal of clinical pharmacology
  • 2011
    • Corpus ID: 19766685
Warfarin combines several characteristics that make it a case study for personalized drug therapy, as follows: it is the most… Expand
Highly Cited
2009
Highly Cited
2009
CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing.
AIMS Although the frequencies of pharmacogenetic variants differ among racial groups, most pharmacogenetic algorithms for… Expand
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  • table 1
  • table 4
2004
2004
Functional impact of CϒP2C9*5, CϒP2C9*6, CϒP2C9*8, and CϒP2C9*11 in vivo among black Africans
Previous data indicate that the urinary losartan/E‐3174 ratio is a marker for cytochrome P450 (CYP) 2C9 activity in vivo. The… Expand
2004
2004
Functional impact of CYP2C95, CYP2C96, CYP2C98, and CYP2C911 in vivo among black Africans.
UNLABELLED Background and aim Previous data indicate that the urinary losartan/E-3174 ratio is a marker for cytochrome P450 (CYP… Expand
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