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CYP2C8*4 Allele
Known as:
CYP2C8, I264M
, Cytochrome P450, Family 2, Subfamily C, Polypeptide 8*4 Allele
, CYP2C8*4
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Human CYP2C8*4 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form of the CYP2C8 wild…
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National Institutes of Health
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Related topics
Related topics
11 relations
10q23.33
Iron Chelation
Metabolic Detoxication, Drug
Metabolism
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
CYP2C8 polymorphism frequencies among Han, Uighur, Hui, and Mongolian Chinese populations.
Xiujun Wu
,
J. Zuo
,
T. Guo
,
Li Yuan
Genetic Testing and Molecular Biomarkers
2013
Corpus ID: 30744911
PURPOSE To determine the allele frequency of three codon-changing variants (CYP2C8*2, CYP2C8*3, and CYP2C8*4) in the Han, Uighur…
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2013
2013
Prevalence of CYP2C8 polymorphisms in a North Indian population.
S. Minhas
,
N. Setia
,
S. Pandita
,
R. Saxena
,
I. Verma
,
S. Aggarwal
Genetics and Molecular Research
2013
Corpus ID: 23786826
CYP2C8 is an important member of the cytochrome P450 family of enzymes; it affects the activity of various drugs used in routine…
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2013
2013
Prevalence of CYP 2 C 8 polymorphisms in a North Indian population
S. Minhas
,
N. Setia
,
S. Pandita
,
R. Saxena
,
I. Verma
,
S. Aggarwal
2013
Corpus ID: 54709601
CYP2C8 is an important member of the cytochrome P450 family of enzymes; it affects the activity of various drugs used in routine…
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2012
2012
Linkage disequilibrium between the CYP2C19*17 allele and other clinically important CYP2C allelic variants in a healthy Scandinavian population
R. Pedersen
,
M. Christensen
,
K. Brøsen
European Journal of Clinical Pharmacology
2012
Corpus ID: 1795939
In a previous study, in three Nordic populations [1], we determined the genotype and allele frequencies of the five most relevant…
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2010
2010
Prevalence of CYP450 gene variations in patients with type 2 diabetes.
A. Weise
,
S. Prause
,
+4 authors
A. Pfützner
Clinical Laboratory
2010
Corpus ID: 36530054
BACKGROUND Drug degradation in the human organism is driven by detoxification mechanisms that can be affected in their efficiency…
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Highly Cited
2008
Highly Cited
2008
Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease
Helen E. Smith
,
J.P. Jones
,
+8 authors
R. Totah
Pharmacogenetics & Genomics
2008
Corpus ID: 20657219
Objectives The calcineurin inhibitors (CNIs) cyclosporine A (CsA) and tacrolimus (Tac) help prevent allograft rejection but are…
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2008
2008
Genetic polymorphisms in breast cancer in relation to risk and prognosis
E. Bågeman
2008
Corpus ID: 70925452
Breast cancer is the most common cancer in women living in Sweden and the second most common cancer in the rest of the world. The…
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Highly Cited
2005
Highly Cited
2005
CYP2C8 polymorphism frequencies among malaria patients in Zanzibar
I. Cavaco
,
J. Strömberg-Nörklit
,
+5 authors
J. Gil
European Journal of Clinical Pharmacology
2005
Corpus ID: 35194878
Objective The determination of the prevalence of the CYP2C8 main alleles in a typical set of malaria patients in Zanzibar, as…
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