Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,145,194 papers from all fields of science
Search
Sign In
Create Free Account
CYC116
Known as:
Aurora Kinase/VEGFR2 Inhibitor CYC116
, CYC 116
, CYC-116
An orally bioavailable small molecule multi-kinase inhibitor with antineoplastic activity. Aurora kinase/VEGFR 2 inhibitor CYC116 inhibits Aurora…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Efectos del sorafenib, un inhibidor tirosina quinasa, en el control del tono vascular
Isabel Pérez Monzó
2018
Corpus ID: 216971421
El carcinoma hepatocelular o hepatocarcinoma (HCC) es uno de los tumores solidos vasculares mas conocidos, representa uno de los…
Expand
2018
2018
Endothelial VEGFR2 KO during CFA induced inflammation is detrimental to murine tibiotalar cartilage integrity
N. Beazley-Long
,
L. Donaldson
2018
Corpus ID: 198381534
Review
2017
Review
2017
Mimetic peptide of ubiquitin-interacting motif of epsin as a cancer therapeutic-perspective in brain tumor therapy through regulating VEGFR2 signaling
Yunzhou Dong
,
Hao Wu
,
+4 authors
Hong Chen
Vessel Plus
2017
Corpus ID: 48355580
Epsins, endocytic adaptor proteins required for internalization of ubiquitylated receptors, are generally upregulated in human…
Expand
2017
2017
Abstract 3090: LY3207447, a tetravalent bispecific antibody targeting VEGFR2 and angiopoietin-2, provides a more efficient anti-angiogenic therapy and an alternative for combination
J. Tetreault
,
Sudhakar Chintharlapalli
,
+10 authors
Ling Liu
2017
Corpus ID: 80555627
Angiopoietin-2 (Ang-2) is released from endothelial cells only in response to stimulus (e.g. wound healing, tumor growth) and…
Expand
2016
2016
Abstract 3262: Effects of lenvatinib mesilate in combination with everolimus on VEGF and FGF-driven angiogenesis and tumor growth
K. Mitsuhashi
,
Takayuki Kimura
,
+10 authors
Y. Funahashi
2016
Corpus ID: 78274900
Lenvatinib mesilate (lenvatinib) is an orally available inhibitor for multiple receptor tyrosine kinases (RTKs) that selectively…
Expand
2015
2015
通心络抑制KK/Upj-Ay小鼠视网膜组织HIF-1a/VEGF/VEGFR-2表达
邢邯英
,
王超
,
张会欣
,
刘敏
,
王杏
2015
Corpus ID: 209155514
目的:观察通心络对自发糖尿病KK/Upj-Ay小鼠视网膜组织缺氧诱导因子-1a(HIF-1a),血管内皮生长因子(VEGF)和血管内皮生长因子受体2(VEGFR2)基因及蛋白表达的影响,探讨通心络对糖尿病视网膜病变的保护机制。方法:40只KK/Upj-Ay…
Expand
2014
2014
Gremlin, un nuevo mediador en la progresión de la enfermedad renal
Lavoz Barría
,
C. Andrea.
2014
Corpus ID: 129570176
Gremlin es un miembro de la superfamilia de TGF?? que actua como antagonista de las proteinas morfogeneticas de hueso (BMPs…
Expand
2013
2013
Ocena ekspresji receptora VEGFR2 w nowotworach złośliwych ślinianek
Latalska Karolina
,
Taran Katarzyna
,
Lewandowska Małgorzata
,
Kobos Józef
2013
Corpus ID: 78190466
2010
2010
An integrated pharmacokinetic–pharmacodynamic model for an Aurora kinase inhibitor
H. Kamei
,
R. Jackson
,
D. Zheleva
,
F. A. Davidson
Journal of Pharmacokinetics and Pharmacodynamics
2010
Corpus ID: 12416495
The spindle assembly checkpoint is a cell cycle surveillance mechanism that ensures the proper separation of chromosomes prior to…
Expand
2008
2008
Systems biology analysis of a novel Aurora kinase inhibitor: CYC116
C. Chassagnole
,
Eric Fernandez
,
+5 authors
D. Fell
2008
Corpus ID: 196561371
1645 Introduction Aurora kinases are known to play a role in mitotic entry, progression and exit. These kinases represent…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE