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CYBB wt Allele

Known as: GP91-1, CGD, NOX2 
Human CYBB wild-type allele is located in the vicinity of Xp21.1 and is approximately 33 kb in length. This allele, which encodes cytochrome B-245… 
National Institutes of Health

Related topics

Related topics

5 relations
Acid-Base EquilibriumAntigen ProcessingCell RespirationIonophore activity

Papers overview

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2019
2019
miR‐141 alleviates LPS‐induced inflammation injury in WI‐38 fibroblasts by up‐regulation of NOX2
Review
2014
Review
2014
Platelet NOX, a novel target for anti-thrombotic treatment
Summary There is a growing body of evidence to suggest that reactive oxidant species (ROS) including O2 −, OH− or H2O2 act as… 
2012
2012
Decreased STAT5 phosphorylation and GATA‐3 expression in NOX2‐deficient T cells: Role in T helper development
Absence of phagocyte NADPH oxidase (NOX2) activity causes chronic granulomatous disease (CGD), a primary immunodeficiency… 
Highly Cited
2009
Highly Cited
2009
Chronic Cocaine-Induced Cardiac Oxidative Stress and Mitogen-Activated Protein Kinase Activation: The Role of Nox2 Oxidase
Chronic cocaine exposure is associated with severe cardiac complications, but the mechanisms of cocaine cardiotoxicity remain… 
Highly Cited
2008
Highly Cited
2008
Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II–Induced Adventitial Myofibroblast Migration
The vascular adventitia is emerging as an important modulator of vessel remodeling. Adventitial myofibroblasts migrate to the… 
Highly Cited
2008
Highly Cited
2008
Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury.
c-Src has been shown to activate NF-kappaB (nuclear factor kappaB) following H/R (hypoxia/reoxygenation) by acting as a redox… 
Highly Cited
2007
Highly Cited
2007
HIV-1 Tat Activates Dual Nox Pathways Leading to Independent Activation of ERK and JNK MAP Kinases*
Human immunodeficiency virus, type 1 Tat is known to exert pleiotropic effects on the vascular endothelium through mitogen… 
Highly Cited
1998
Highly Cited
1998
Correction of respiratory burst activity in X-linked chronic granulomatous cells to therapeutically relevant levels after gene transfer into bone marrow CD34+ cells.
Chronic granulomatous disease (CGD) is a disorder of the lymphohematopoietic system, whereby phagocytes of affected patients are… 
Highly Cited
1995
Highly Cited
1995
The Arachidonate-activable, NADPH Oxidase-associated H Channel
The human neutrophil NADPH oxidase-associated H channel acts as a charge compensator for the electrogenic generation of… 
1993
1993
X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox.
Chronic granulomatous disease (CGD) is an inherited immunodeficiency resulting from the inability of an individual's phagocytes… 
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