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CYBB wt Allele

Known as: GP91-1, CGD, NOX2 
Human CYBB wild-type allele is located in the vicinity of Xp21.1 and is approximately 33 kb in length. This allele, which encodes cytochrome B-245… 
National Institutes of Health

Related topics

Related topics

5 relations
Acid-Base EquilibriumAntigen ProcessingCell RespirationIonophore activity

Papers overview

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Highly Cited
2016
Highly Cited
2016
NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury
Highly Cited
2010
Highly Cited
2010
Mechanisms Contributing to Cerebral Infarct Size after Stroke: Gender, Reperfusion, T Lymphocytes, and Nox2-Derived Superoxide
Cerebral infarct volume is typically smaller in premenopausal females than in age-matched males after ischemic stroke, but the… 
Highly Cited
2007
Highly Cited
2007
Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase
All methods used for quantitation of superoxide have limitations when it comes to differentiating between extracellular and… 
Highly Cited
2006
Highly Cited
2006
NOX2 and NOX4 mediate proliferative response in endothelial cells.
Increased levels of reactive oxygen species (ROS) contribute to many cardiovascular diseases. In neutrophils, ROS are generated… 
Highly Cited
2005
Highly Cited
2005
Expression and localization of NOX2 and NOX4 in primary human endothelial cells.
Reactive oxygen species (ROS) control the integrity of the vascular endothelium. Our laboratory has recently shown that… 
Highly Cited
2005
Highly Cited
2005
Point Mutations in the Proline-rich Region of p22phox Are Dominant Inhibitors of Nox1- and Nox2-dependent Reactive Oxygen Generation*
The integral membrane protein p22phox is an indispensable component of the superoxide-generating phagocyte NADPH oxidase, whose… 
Highly Cited
2000
Highly Cited
2000
Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice.
Superoxide, the reduced form of molecular oxygen, has been implicated in the genesis of vascular disease. One potential mechanism… 
Highly Cited
2000
Highly Cited
2000
Gene therapy of chronic granulomatous disease
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder which results from absence or malfunction of the… 
Review
1996
Review
1996
Interactions between the components of the human NADPH oxidase: intrigues in the phox family.
Highly Cited
1992
Highly Cited
1992
Cytochrome b558, a component of the phagocyte NADPH oxidase, is a flavoprotein.
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