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CXC 195

Known as: CXC-195, CXC195 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

PiperazinesPyrazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Tetramethylpyrazine Analogue CXC195 Protects Against Dopaminergic Neuronal Apoptosis via Activation of PI3K/Akt/GSK3β Signaling Pathway in 6-OHDA-Induced Parkinson’s Disease Mice
Parkinson’s disease (PD) is a progressive neurodegenerative disorder and characterized by motor system disorders resulting in… 
2016
2016
Tetramethylpyrazine Analogue CXC195 Protects Against Dopaminergic Neuronal Apoptosis via Activation of PI3K/Akt/GSK3β Signaling Pathway in 6-OHDA-Induced Parkinson’s Disease Mice
Parkinson’s disease (PD) is a progressive neurodegenerative disorder and characterized by motor system disorders resulting in… 
Highly Cited
2015
Highly Cited
2015
CXC195 suppresses proliferation and inflammatory response in LPS-induced human hepatocellular carcinoma cells via regulating TLR4-MyD88-TAK1-mediated NF-κB and MAPK pathway.
Review
2015
Review
2015
Ligustrazine monomer against cerebral ischemia/reperfusion injury
Ligustrazine (2,3,5,6-tetramethylpyrazine) is a major active ingredient of the Szechwan lovage rhizome and is extensively used in… 
2015
2015
IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to CXC195-induced apoptosis in human bladder carcinoma T24 cells.
Highly Cited
2014
Highly Cited
2014
Tetramethylpyrazine analogue CXC195 protects against cerebral ischemia/reperfusion-induced apoptosis through PI3K/Akt/GSK3β pathway in rats
2014
2014
Tetramethylpyrazine Analogue CXC195 Ameliorates Cerebral Ischemia–reperfusion Injury by Regulating Endothelial Nitric Oxide Synthase Phosphorylation Via PI3K/Akt Signaling
A novel tetramethylpyrazine derivative, CXC195, has been recently shown to protect against cerebral ischemia–reperfusion (I/R… 
2013
2013
Tetramethylpyrazine Analogue CXC195 Protects against Cerebral Ischemia/Reperfusion Injury in the Rat by an Antioxidant Action via Inhibition of NADPH Oxidase and iNOS Expression
Aims: This study was conducted to investigate the protective effects of CXC195, a tetramethylpyrazine analogue, in acute focal… 
2013
2013
Pharmacokinetics of a New Tetramethylpyrazine Analogue CXC195 in Rats
Abstract Objective: To investigate the pharmacokinetical characteristics of a new neuroprotective drug CXC195 after… 
2010
2010
Mechanism of tetramethylpyrazine analogue CXC195 inhibition of hydrogen peroxide-induced apoptosis in human endothelial cells.
A tetramethylpyrazine analogue, CXC195, was synthesized by the Boekelheide reaction, in which the second methyl group of… 
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