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CRX-526
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Glucosamine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Toll-like Rezeptor 4-Blockade bei experimenteller Endotoxinämie
M. Harloff
2018
Corpus ID: 196571997
Im Rahmen der Sepsis besitzt die Mikrozirkulation und insbesondere die intestinale Mikrozirkulation eine tragende Rolle in Bezug…
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2017
2017
Anti-inflammatory effect of miltirone on inflammatory bowel disease via TLR4/NF-κB/IQGAP2 signaling pathway.
H. Wang
,
Junfei Gu
,
+9 authors
Liang Feng
Biomedicine & pharmacotherapy = Biomedecine…
2017
Corpus ID: 11696507
Inflammatory bowel disease (IBD) is characterized by a radical imbalance in the activation of proinflammatory and anti…
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2015
2015
Experimental TLR4 inhibition improves intestinal microcirculation in endotoxemic rats.
J. Zhou
,
M. Soltow
,
K. Zimmermann
,
D. Pavlović
,
B. Johnston
,
C. Lehmann
Microvascular research
2015
Corpus ID: 25607517
INTRODUCTION Toll like receptor 4 (TLR4) represents a critical cellular link for endotoxin-induced pathology. The aim of this…
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2014
2014
The TLR4/NF-κB signaling pathway mediates the growth of colon cancer.
H-Y Huang
,
Z-J Zhang
,
+5 authors
J. Qian
European review for medical and pharmacological…
2014
Corpus ID: 30930292
OBJECTIVE We studied the involvement of the TLR4/NF-κB pathway in the growth of colon cancer using human colon cancer specimens…
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2014
2014
There is an increasing trend in the The TLR 4 / NF-κ B signaling pathway mediates the growth of colon cancer
H.-Y. Huang
,
Z.-j. Zhang
,
+5 authors
J. QIAN Suizhou
2014
Corpus ID: 16087000
3834 Abstract. – OBJECTIVE: We studied the involvement of the TLR4/NF-κB pathway in the growth of colon cancer using human colon…
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Highly Cited
2013
Highly Cited
2013
The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy.
Miao Lin
,
W. Yiu
,
+6 authors
S. Tang
Kidney international
2013
Corpus ID: 25019542
We recently showed that Toll-like receptor (TLR) TLR4 was overexpressed in the human diabetic kidney, which could promote tubular…
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2010
2010
The TLR4 antagonist CRX-526 reduces LPS-induced leukocyte activation and improves capillary perfusion of the rat intestine
M. Soltow
,
K. Zimmermann
,
+6 authors
C. Lehmann
Critical Care
2010
Corpus ID: 47036801
Toll-like receptor 4 (TLR4) represents an important mediator of endotoxin-related signal transduction. The aim of our study was…
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Highly Cited
2009
Highly Cited
2009
Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema.
G. Zanotti
,
Monica Casiraghi
,
+8 authors
T. Egan
American journal of physiology. Lung cellular and…
2009
Corpus ID: 403435
Toll-like receptors (TLRs) of the innate immune system contribute to noninfectious inflammatory processes. We employed a murine…
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2008
2008
The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.
Hélène G. Bazin
,
T. Murray
,
+10 authors
D. Johnson
Bioorganic & medicinal chemistry letters
2008
Corpus ID: 24804833
To overcome the chemical and metabolic instability of the secondary fatty acyl residues in the AGP class of lipid A mimetics, the…
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Highly Cited
2005
Highly Cited
2005
A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease 1
M. Fort
,
A. Mozaffarian
,
+10 authors
R. Hershberg
The Journal of Immunology
2005
Corpus ID: 34120776
Current evidence indicates that the chronic inflammation observed in the intestines of patients with inflammatory bowel disease…
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