Skip to search formSkip to main contentSkip to account menu

CRB2 gene

Known as: CRB2, crumbs 2, cell polarity complex component, FLJ38464 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Phase stability and elastic properties of chromium borides with various stoichiometries.
Phase stability is important to the application of materials. By first-principles calculations, we establish the phase stability… 
2010
2010
BRCT Domain Interactions with Phospho-Histone H2A Target Crb2 to Chromatin at Double-Strand Breaks and Maintain the DNA Damage Checkpoint
ABSTRACT Relocalization of checkpoint proteins to chromatin flanking DNA double-strand breaks (DSBs) is critical for cellular… 
Highly Cited
2008
Highly Cited
2008
Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair.
Schizosaccharomyces pombe Crb2 is a checkpoint mediator required for the cellular response to DNA damage. Like human 53BP1 and… 
Highly Cited
2008
Highly Cited
2008
Di-methyl H4 Lysine 20 Targets the Checkpoint Protein Crb2 to Sites of DNA Damage*
Histone lysine methylation is an important chromatin modification that can be catalyzed to a mono-, di-, or tri-methyl state. An… 
2007
2007
The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA
DNA damage checkpoints are signal transduction pathways that are activated after genotoxic insults to protect genomic integrity… 
Highly Cited
2006
Highly Cited
2006
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.
Cellular responses to DNA damage involve the relocalization of checkpoint proteins to DNA double-strand breaks (DSBs). The… 
Highly Cited
2004
Highly Cited
2004
Histone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast
ABSTRACT Mammalian ATR and ATM checkpoint kinases modulate chromatin structures near DNA breaks by phosphorylating a serine… 
Highly Cited
2004
Highly Cited
2004
Regulation of checkpoint kinases through dynamic interaction with Crb2
ATR/Rad3‐like kinases promote the DNA damage checkpoint through regulating Chk1 that restrains the activation of cyclin‐dependent… 
Highly Cited
2003
Highly Cited
2003
Retention but Not Recruitment of Crb2 at Double-Strand Breaks Requires Rad1 and Rad3 Complexes
ABSTRACT The fission yeast checkpoint protein Crb2, related to budding yeast Rad9 and human 53BP1 and BRCA1, has been suggested… 
Highly Cited
1997
Highly Cited
1997
Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.
Fission yeast Cut5/Rad4 plays a unique role in the genome maintenance as it is required for replication, replication checkpoint… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)