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CR011

National Institutes of Health

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Glembatumumab

Papers overview

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2016
2016
Abstract 4209: Targeting GPNMB with 89Zr-CR011 for PET imaging of triple negative breast cancer
Glycoprotein non-metastatic melanoma B (GPNMB) is a transmembrane protein overexpressed in 30 - 40% of triple negative breast… 
2010
2010
Correlation of GPNMB expression with outcome in breast cancer (BC) patients treated with the antibody–drug conjugate (ADC), CDX-011 (CR011-vcMMAE).
1095 Background: GPNMB (osteoactivin), a novel glycoprotein expressed in 25-40% of breast cancers as well as various tumor types… 
2010
2010
Frequent dosing and GPNMB expression with CDX-011 (CR011-vcMMAE), an antibody-drug conjugate (ADC), in patients with advanced melanoma.
8525 Background: CDX-011 is an ADC consisting of the potent cellular toxin MMAE conjugated to a fully human monoclonal antibody… 
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