Glembatumumab

Known as: Immunoglobulin G2, Anti-(Human Transmembrane Glycoprotein NMB (HGFIN) Extracellular Domain) Human Monoclonal CR011 Heavy Chain (133-215')-Disulfide with Human Monoclonal CR011 Kappa Light Chain, Dimer (221-221'':222-222'':225-225'':228- 228'')-Tetrakis, Immunoglobulin, Anti-(Human Glycoprotein NMB Extracellular Domain) (Human Monoclonal CR011 Heavy Chain), Disulfide with Human Monoclonal CR011 Gamma-2 Kappa-Chain, Dimer 
A human monoclonal antibody against transmembrane glycoprotein non-metastatic melanoma protein B (GPNMB). Glembatumumab binds to GPNMB on cancer… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2016
012319872016

Papers overview

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Review
2017
Review
2017
Oncogene-targeted therapy is a major component of precision oncology, and although patients with metastatic melanoma have… (More)
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2017
2017
High levels of expression of glycoprotein non-metastatic B (gpNMB) in triple negative breast cancer (TNBC) and its association… (More)
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2016
2016
BACKGROUND Cure rates for children and young adults with osteosarcoma have remained stagnant over the past three decades… (More)
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2015
2015
PURPOSE Glycoprotein NMB (gpNMB), a negative prognostic marker, is overexpressed in multiple tumor types. Glembatumumab vedotin… (More)
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2014
2014
PURPOSE The antibody-drug conjugate glembatumumab vedotin links a fully human immunoglobulin G2 monoclonal antibody against the… (More)
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2014
2014
PURPOSE Glycoprotein NMB (gpNMB), a novel transmembrane protein overexpressed in 40% to 60% of breast cancers, promotes… (More)
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2014
2014
BACKGROUND Glembatumumab vedotin is an antibody-auristatin conjugate that targets cells expressing the transmembrane glycoprotein… (More)
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2010
2010
Glembatumumab vedotin (CR-011-vc-MMAE) is a mAb-drug conjugate being developed by Celldex Therapeutics Inc for the treatment of… (More)
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1996
1996
BACKGROUND Atracurium has four chiral centers and the marketed product is a mixture of ten optical and geometric isomers. Six of… (More)
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1987
1987
Neisseria meningitidis group B strain M986 (serotypes 2a, 7) (NMB) elicits a specific primary antiphosphorylcholine immune… (More)
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