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CP 45634

Known as: CP 45,634, CP-45,634, CP-45634 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

sorbinil

Papers overview

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Highly Cited
1988
Highly Cited
1988
Spiro hydantoin aldose reductase inhibitors.
Sorbitol formation from glucose, catalyzed by the enzyme aldose reductase, is believed to play a role in the development of… 
1986
1986
Studies of aldose reductase using neuronal cell culture and ligated rat sciatic nerve.
1982
1982
Inhibition of Human Brain Aldose Reductase and Hexonate Dehydrogenase by Alrestatin and Sorbinil
Abstract: Human brain aldose reductase and hexonate dehydrogenase are inhibited by alrestatin (AY 22,284) and sorbinil (CP 45,634… 
Highly Cited
1979
Highly Cited
1979
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats.
1979
1979
Inhibition of polyol pathway activity in diabetic and galactosemic rats by the aldose reductase inhibitor CP-45,634.
Studies in animal models and man suggest that conversion of glucose to sorbitol via the polyol pathway may be causative in the… 
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