COUP Transcription Factor I

Known as: COUP TFI Protein, COUP TF1 Protein, COUP Transcription Factor I [Chemical/Ingredient] 
A COUP transcription factor that was originally identified as a homodimer that binds to a direct repeat regulatory element in the chicken albumin… (More)
National Institutes of Health

Related topics

Related topics

11 relations
In BloodNR2F1 geneNuclear Receptor Subfamily 1, Group F, Member 2Process of secretion
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Nr2f1 protein, rat

Papers overview

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Highly Cited
2010
Highly Cited
2010
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.
The lymphatic system plays a key role in tissue fluid homeostasis. Lymphatic dysfunction contributes to the pathogenesis of many… (More)
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Highly Cited
2009
Highly Cited
2009
COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.
Wnt signaling through beta-catenin and TCF maintains preadipocytes in an un-differentiated proliferative state; however, the… (More)
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2009
2009
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum.
COUP-TFII (also known as Nr2f2), a member of the nuclear orphan receptor superfamily, is expressed in several regions of the… (More)
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Highly Cited
2008
Highly Cited
2008
Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated Receptor
The chicken ovalbumin upstream promoter-transcription factors (COUP-TFI and II) make up the most conserved subfamily of nuclear… (More)
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Highly Cited
2005
Highly Cited
2005
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
Arteries and veins are anatomically, functionally and molecularly distinct. The current model of arterial–venous identity… (More)
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Highly Cited
2005
Highly Cited
2005
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia.
Congenital diaphragmatic hernia (CDH), a life-threatening anomaly, is a major cause of pediatric mortality. Although the disease… (More)
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Highly Cited
2001
Highly Cited
2001
Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.
Hepatocyte nuclear factor 4alpha (HNF-4alpha) (nuclear receptor 2A1) is an essential regulator of hepatocyte differentiation and… (More)
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Highly Cited
2000
Highly Cited
2000
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).
The gene for cholesterol 7alpha-hydroxylase (CYP7A1) contains a sequence at nt -149 to -118 that was found to play a large role… (More)
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Highly Cited
1999
Highly Cited
1999
The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development.
The embryonic expression of COUP-TFII, an orphan nuclear receptor, suggests that it may participate in mesenchymal-epithelial… (More)
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Highly Cited
1997
Highly Cited
1997
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program.
During cardiac hypertrophy, the chief myocardial energy source switches from fatty acid beta-oxidation (FAO) to glycolysis-a… (More)
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