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COPS6 wt Allele

Known as: MOV34 Homolog, 34 kD Gene, COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) Gene, COP9 Signalosome Subunit 6 wt Allele 
Human COPS6 wild-type allele is located in the vicinity of 7q22.1 and is approximately 3 kb in length. This allele, which encodes COP9 signalosome… 
National Institutes of Health

Related topics

Related topics

3 relations
7q22.1DeubiquitinationSignal Transduction

Papers overview

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2018
2018
Downregulation of CSN6 attenuates papillary thyroid carcinoma progression by reducing Wnt/β‐catenin signaling and sensitizes cancer cells to FH535 therapy
The incidence of thyroid cancer has increased worldwide at a rate higher than that of any other cancer. CSN6 is overexpressed in… 
Highly Cited
2016
Highly Cited
2016
Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis
Constitutive photomorphogenesis 9 signalosome (CSN) consists of a total of eight subunits (CSN1-CSN8) in mammalian cells. CSN6… 
2016
2016
CSN6, a subunit of the COP9 signalosome, is involved in early response to iron deficiency in Oryza sativa
The COP9 signalosome (CSN) plays an important role in proteasome-mediated degradation by regulating CUL1 rubylation of the SCF… 
Highly Cited
2015
Highly Cited
2015
An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation.
2015
2015
Regulating the stability and localization of CDK inhibitor p27Kip1 via CSN6-COP1 axis
The COP9 signalosome subunit 6 (CSN6), which is involved in ubiquitin-mediated protein degradation, is overexpressed in many… 
Review
2015
Review
2015
The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair
The maintenance of genomic integrity is an important process in organisms as failure to sense and repair damaged DNA can result… 
2013
2013
Spatial Remapping in the Audio-tactile Ventriloquism Effect: A TMS Investigation on the Role of the Ventral Intraparietal Area
Previous studies have suggested that the putative human homologue of the ventral intraparietal area (hVIP) is crucially involved… 
2008
2008
The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis
In concert with the ubiquitin (Ub) proteasome system (UPS) the COP9 signalosome (CSN) controls the stability of cellular… 
2007
2007
The Subunit CSN6 of the COP9 Signalosome Is Cleaved during Apoptosis*
The COP9 signalosome is a large multiprotein complex that consists of eight subunits termed CSN1–CSN8. The diverse functions of… 
2002
2002
Carboxyl Terminus of hVIP/mov34 Is Critical for HIV-1-Vpr Interaction and Glucocorticoid-mediated Signaling*
Human immunodeficiency virus, type 1 (HIV-1)vpr is a highly conserved gene among lentiviruses. The diverse functions of Vpr… 
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