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COPS5 gene

Known as: COPS5, JAB1, COP9 signalosome subunit 5 
National Institutes of Health

Related topics

Related topics

1 relation
COPS3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
JAB1/CSN5: a new player in cell cycle control and cancer
Abstractc-Jun activation domain-binding protein-1 (Jab1) acts as a modulator of intracellular signaling and affects cellular… 
Highly Cited
2007
Highly Cited
2007
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation.
A major adaptive pathway for hypoxia is hypoxic preconditioning (HPC), a form of endogenous protection that renders cells… 
Highly Cited
2006
Highly Cited
2006
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity.
Highly Cited
2005
Highly Cited
2005
Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1.
Vitamin D3 up-regulated protein 1 (VDUP1) is a stress-response gene that is up-regulated by 1,25(OH)2D3 in many cells. It has… 
Highly Cited
2002
Highly Cited
2002
Jab1 Interacts Directly with HIF-1α and Regulates Its Stability*
Hypoxia-inducible factor-1 (HIF-1) is a master transcription factor that controls transcriptional activation of a number of genes… 
Review
2001
Review
2001
JAB1/CSN5 and the COP9 signalosome
The Jun activating binding protein (JAB1) specifically stabilizes complexes of c‐Jun or JunD with AP‐1 sites, increasing the… 
Highly Cited
2000
Highly Cited
2000
JAB1 Interacts with Both the Progesterone Receptor and SRC-1*
JAB1 (Jun activation domain-binding protein-1) has previously been described as a coactivator of AP1 transcription factor. We… 
Highly Cited
1999
Highly Cited
1999
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
The proliferation of mammalian cells is under strict control, and the cyclin-dependent-kinase inhibitory protein p27Kip1 is an… 
Highly Cited
1998
Highly Cited
1998
Arabidopsis Homologs of a c-Jun Coactivator Are Present Both in Monomeric Form and in the COP9 Complex, and Their Abundance Is Differentially Affected by the Pleiotropic cop/det/fus Mutations
The CONSTITUTIVE PHOTOMORPHOGENIC9 (COP9) complex is a nuclear localized, multisubunit protein complex essential for repression… 
Highly Cited
1997
Highly Cited
1997
Structure of cDNAs Encoding Human Eukaryotic Initiation Factor 3 Subunits
The mammalian translation initiation factor 3 (eIF3), is a multiprotein complex of ∼600 kDa that binds to the 40 S ribosome and… 
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