Skip to search formSkip to main contentSkip to account menu

COPS5 gene

Known as: COPS5, JAB1, COP9 signalosome subunit 5 
National Institutes of Health

Related topics

Related topics

1 relation
COPS3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells.
2008
2008
JAB1 accelerates mitochondrial apoptosis by interaction with proapoptotic BclGs.
2007
2007
Jab1 mediates protein degradation of the Rad9-Rad1-Hus1 checkpoint complex.
Highly Cited
2006
Highly Cited
2006
Jab1 Induces the Cytoplasmic Localization and Degradation of p53 in Coordination with Hdm2*
The biological mechanisms for maintaining the basal level of p53 in normal cells require nuclear exclusion and cytoplasmic… 
Highly Cited
2004
Highly Cited
2004
Immunohistochemical study of Skp2 and Jab1, two key molecules in the degradation of P27, in lung adenocarcinoma
To clarify the association of the P27 degradation pathway proteins, Skp2 and Jab1, with the development and progression of lung… 
2004
2004
JAB1 enhances HAND2 transcriptional activity by regulating HAND2 DNA binding
HAND2 (also known as dHAND) is a basic helix‐loop‐helix (bHLH) transcription factor essential for development of the heart, limbs… 
Highly Cited
2003
Highly Cited
2003
Skp2 and Jab1 Expression Are Associated with Inverse Expression of p27KIP1 and Poor Prognosis in Oral Squamous Cell Carcinomas
Previous studies have shown that low levels of p27KIP1, an inhibitor of G1 cyclin-dependent kinases (CDK), are associated with… 
Highly Cited
2002
Highly Cited
2002
Jab1 Interacts Directly with HIF-1α and Regulates Its Stability*
Hypoxia-inducible factor-1 (HIF-1) is a master transcription factor that controls transcriptional activation of a number of genes… 
Highly Cited
2002
Highly Cited
2002
The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway
VHL is part of an SCF related E3-ubiquitin ligase complex with ‘gatekeeper’ function in renal carcinoma. However, no mutations… 
2000
2000
Characterization of the mouse JAB1 cDNA and protein.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)