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COLLAGEN-LIKE ALZHEIMER AMYLOID PLAQUE COMPONENT

Known as: CLAC 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2016
012319732016

Papers overview

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2014
2014
Closed-loop automatic oxygen control (CLAC) in preterm infants: a randomized controlled trial.
BACKGROUND AND OBJECTIVE In preterm infants receiving supplemental oxygen, routine manual control (RMC) of the fraction of… (More)
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2011
2011
Association of contact lens-related allergic conjunctivitis with changes in the morphology of meibomian glands
To observe morphological changes in the meibomian glands of patients with contact lens-related allergic conjunctivitis (CLAC) and… (More)
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2010
2010
Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates*
Supplemental Figure 2. (A) S1 cells (γ-30 based cells that also stably overexpress NCT-GST) were crosslinked with DSP or DMSO… (More)
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Highly Cited
2005
Highly Cited
2005
A method for calling gains and losses in array CGH data.
Array CGH is a powerful technique for genomic studies of cancer. It enables one to carry out genome-wide screening for regions of… (More)
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2005
2005
Pen-2 is incorporated into the gamma-secretase complex through binding to transmembrane domain 4 of presenilin 1.
gamma-Secretase is a multimeric membrane protein complex comprised of presenilin (PS), nicastrin (Nct), Aph-1, and Pen-2. It is a… (More)
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2005
2005
CLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrils.
CLAC (collagenous Alzheimer amyloid plaque component) is a proteolytic fragment derived from a novel membrane-bound collagen… (More)
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2005
2005
Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site.
Amyloid beta-peptide (Abeta) deposition into amyloid plaques is one of the invariant neuropathological features of Alzheimer's… (More)
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2005
2005
Collagenous Alzheimer amyloid plaque component assembles amyloid fibrils into protease resistant aggregates.
Recently, a novel plaque-associated protein, collagenous Alzheimer amyloid plaque component (CLAC), was identified in brains from… (More)
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2002
2002
CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV.
We raised monoclonal antibodies against senile plaque (SP) amyloid and obtained a clone 9D2, which labeled amyloid fibrils in SPs… (More)
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1983
1983
Towards purification of the scrapie agent.
A method for the partial purification of scrapie infectivity from hamster brain is described. About a 100-1000-fold, 20-fold, and… (More)
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