CLCN7 protein, human

Known as: CLC-7 chloride channel protein, human, Chloride Channel 7 Alpha Subunit, CLCN7 
H(+)/Cl(-) exchange transporter 7 (805 aa, ~89 kDa) is encoded by the human CLCN7 gene. This protein plays a role in proton-coupled, chloride anion… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
0519982018

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2014
2014
Osteopetrosis is an inherited disorder of impaired bone resorption, with the most commonly affected genes being CLCN7 and TCIRG1… (More)
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2012
2012
Osteopetrosis is a group of genetic bone disorders. There are three types of osteopetrosis: autosomal recessive osteopetrosis… (More)
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2010
2010
During lysosomal acidification, proton-pump currents are thought to be shunted by a chloride ion (Cl-) channel, tentatively… (More)
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2009
2009
Osteoclasts are multinucleated bone-resorbing cells responsible for constant remodeling of bone tissue and for maintaining… (More)
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2006
2006
CONTEXT Genetic factors are important determinants of bone mineral density (BMD). The fact that mutations in the ClC-7 chloride… (More)
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2005
2005
UNLABELLED Here we show that a common polymorphism causing a valine to methionine amino acid substitution at codon 418 (V418M) in… (More)
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2004
2004
UNLABELLED We studied osteoclastic differentiation from normal and osteopetrotic human CD14 cells in vitro. Defects in acid… (More)
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2004
2004
Autosomal recessive malignant infantile osteopetrosis (ARO) is characterized by severe osteosclerosis, pathologic fractures… (More)
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2002
2002
Osteopetrosis is a heterogeneous group of inherited disorders that includes a malignant autosomal recessive form, an intermediate… (More)
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1999
1999
The CLC family of voltage-gated chloride channels comprises nine members in mammals. CLCN6 and CLCN7 belong to a novel, poorly… (More)
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