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CI 994

Known as: CI-994, CI994 
National Institutes of Health

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1 relation

Broader (1)

acetyldinaline

Papers overview

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2018
2018
The Histone Deacetylase Inhibitor, CI994, Improves Nuclear Reprogramming and In Vitro Developmental Potential of Cloned Pig Embryos.
Epigenetic reprogramming and somatic cell nuclear transfer (SCNT) cloning efficiency were recently enhanced using histone… 
2016
2016
Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation
The aberrant expression of human sodium iodide symporter (NIS) in breast cancer (BC) has raised the possibility of using targeted… 
2013
2013
Class I HDAC imaging using [3H]CI-994 autoradiography
[3H]CI-994, a radioactive isotopologue of the benzamide CI-994, a class I histone deacetylase inhibitor (HDACi), was evaluated as… 
2013
2013
FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors
2008
2008
CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo.
N-acetyl-dinaline (CI-994) is an investigational anti-cancer drug which inhibits histone deacetylases. We evaluated the… 
2004
2004
Preclinical toxicity of a new oral anticancer drug, CI-994 (Acetyldinaline), in rats and dogs
CI-994 (acetyldinaline) is an orally active anticancer drug currently in Phase 1 clinical trials. To assess int preclinical… 
2004
2004
Preclinical pharmacokinetic, antitumor and toxicity studies with CL-994 (N-acetyldinaline)
CI-994, a substituted benzamide derivative, is a compound that showed solid tumor selectivity for a variety of solid tumor models… 
2000
2000
Pharmacokinetics and cerebrospinal fluid penetration of CI-994 (N-acetyldinaline) in the nonhuman primate.
CI-994 is a substituted benzamide derivative that has demonstrated significant antitumor activity in vitro and in vivo against a… 
1999
1999
Immunotoxicity of the anticancer drug CI-994 in rats: effects on lymphoid tissue
Abstract CI-994 (acetyldinaline) is an investigative oral anticancer drug currently in clinical trials. To characterize the… 
1995
1995
Role of a small molecular weight phosphoprotein in the mechanism of action of CI‐994 (N‐acetyldinaline)
The mechanism of action of the novel anti‐cancer compound CI‐994 was studied in C26 murine colon tumor and HCT‐8 human colon… 
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