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CI-990

 
National Institutes of Health

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1 relation
PD 131112

Papers overview

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1998
1998
Bacterial eradication by clinafloxacin, CI-990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies.
Bactericidal activities of clinafloxacin, CI-990 and ciprofloxacin were examined and compared for a small collection of gram… Expand
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1995
1995
In vitro and in vivo activities of clinafloxacin, CI-990 (PD 131112), and PD 138312 versus enterococci.
Certain new fluoroquinolones have high activity against enterococci. Against Enterococcus faecalis (n = 18), MICs at which 90% of… Expand
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1995
1995
Efficacy of quinolones in preventing Staphylococcus aureus-induced abscess in mice.
The new fluoroquinolones clinafloxacin, CI-990 (PD 131112/PD 131628), sparfloxacin, and PD 138312 were bactericidal against… Expand
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1994
1994
Quinolone therapy in the prevention of endogenous and exogenous infection after irradiation.
The effect of oral therapy with 6 quinolones, lomefloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, and CI-990 in the… Expand
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1993
1993
Comparative in-vitro activities of the new quinolone, Bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, CI-960 and CI-990.
The in-vitro activity of the new quinolone, Bay y 3118, was compared with that of ciprofloxacin, tosufloxacin, sparfloxacin, CI… Expand
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1993
1993
CI-990 (PD 131112): A new quinolone prodrug.
In vitro susceptibility of 1021 strains of recent clinical isolates was determined against the new fluoroquinolone CI-990 (PD… Expand
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Review
1993
Review
1993
Patterns of susceptibility to fluoroquinolones among anaerobic bacterial isolates in the United States.
The activity of the fluoroquinolone antibiotics against anaerobic bacteria has generally been moderate to poor. Nalidixic acid… Expand
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1992
1992
Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria.
The in vitro activities of seven fluoroquinolones against 290 anaerobes were determined by agar dilution. CI-960 and WIN 57273… Expand
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1992
1992
Comparative Activity ofCiprofloxacin, Ofloxacin, Sparfloxacin, Temafloxacin, CI-960, CI-990, andWIN 57273against
(AT4140,RP64206, andPD131501), CI-960(PD127391 andAM1091)[7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6fluoro-1,4-dihydro-4… Expand
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1991
1991
In vitro studies with five quinolones: evidence for changes in relative potency as quinolone resistance rises.
A panel of 203 staphylococci, Enterobacteriaceae, Pseudomonas aeruginosa, and miscellaneous nonfermentative gram-negative bacilli… Expand
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