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CI 977

Known as: CI-977 
National Institutes of Health

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enadoline

Papers overview

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2001
2001
Quantitative autoradiographic mapping of the ORL1, mu-, delta- and kappa-receptors in the brains of knockout mice lacking the ORL1 receptor gene.
Until recently the opioid receptor family was thought to consist of only the mu-, delta- and kappa-receptors. The cloning of… 
1999
1999
Effects of Neonatal Naltrindole Treatment on Antinociceptive and Behavioral Responses to μ and k Agonists in Rats
1999
1999
Behavioral evaluation of visceral pain in a rat model of colonic inflammation.
A new rat model was established up to evaluate the antinociceptive effect of compounds in visceral pain. The test consisted in… 
1998
1998
The discriminative stimulus properties of U50,488 and morphine are not shared by fedotozine
1998
1998
Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists.
The three-dimensional structure, dynamics, and binding modes of representative kappa-opioid agonists of the arylacetamide class… 
1996
1996
Search for the Pharmacophore in Kappa‐agonistic Diazabicyclo[3.3.1]nonan‐9‐one‐1,5‐diesters and Arylacetamides
Several heterocyclic bicyclo[3.3.1]nonan‐9‐ones were found to have a high affinity to k opioid receptors. 3,7… 
Highly Cited
1993
Highly Cited
1993
Pharmacological modification of glutamate neurotoxicity in vivo
1992
1992
A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro.
Intracellular recordings were made from neurons in a rat locus coeruleus slice preparation in vitro. A postsynaptic potential was… 
Review
1992
Review
1992
Neuropeptides. Function and clinical applications.
Neuropeptides are the most abundant chemical messengers in the brain and their major role seems to be the modulation of amine and… 
1990
1990
The anticonvulsant action of CI-977, a selective kappa-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex.
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