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CI 977

Known as: CI-977 
 
National Institutes of Health

Papers overview

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Highly Cited
1998
Highly Cited
1998
This study examined the effects of intrathecally (i.t.) administered mu and delta opioid receptor agonists on the flinching… Expand
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Highly Cited
1995
Highly Cited
1995
Antinociceptive effects of systemically or locally administered opioid mu, kappa and delta agonists were evaluated in a rat model… Expand
Highly Cited
1994
Highly Cited
1994
The diuretic effects, pharmacokinetics, and safety of CI‐977, a new centrally acting selective kappa‐opioid agonist, were… Expand
Highly Cited
1994
Highly Cited
1994
The selective kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) has been shown to modulate cannabinoid-induced… Expand
1993
1993
The effects of the kappa-1 opioid receptor agonist (5R)-(5 alpha,7 alpha,8 beta)-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4,5… Expand
1993
1993
The effects of the kappa-1 opioid agonist CI-977 upon the volume of ischemic brain damage (defined using quantitative… Expand
Highly Cited
1992
Highly Cited
1992
The effect of a novel, highly potent and selective kappa-opioid receptor agonist CI-977 upon ischaemic brain damage and brain… Expand
1992
1992
CI-977 is a selective, nonpeptide kappa opioid agonist. In rhesus monkeys, CI-977 is a potent antinociceptive agent against… Expand
Highly Cited
1990
Highly Cited
1990
1 CI‐977 is a new, nonpeptide κ‐opioid compound that has been synthesized and its pharmacological properties determined in a… Expand
1990
1990
The selective kappa-opioid receptor agonist CI-977, stereoselectively antagonised clonic seizures induced by slow i.v. infusion… Expand