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CI 1040

Known as: CI-1040, CI1040 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
There is no cure for osteoarthritis—the most common disease of the joints. By piecing together the molecular events that drive… 
Highly Cited
2009
Highly Cited
2009
Objective—Abdominal aortic aneurysm (AAA) is a life-threatening disease affecting almost 10% of the population over age 65… 
Highly Cited
2008
Highly Cited
2008
The epidermal growth factor receptor (EGFR) inhibitor erlotinib is approved for treatment of pancreatic cancer but the overall… 
Highly Cited
2008
Highly Cited
2008
Highly Cited
2007
Highly Cited
2007
CONTEXT Targeting MAPK kinase (MEK) in the MAPK pathway is a potentially effective therapeutic strategy for thyroid cancer… 
Highly Cited
2006
Highly Cited
2006
Type 1 neurofibromatosis (NF1) is a common autosomal dominant disorder that results in neuroectodermal tumors. The NF1 tumor… 
Highly Cited
2005
Highly Cited
2005
PURPOSE This phase I study was undertaken to define the toxicity, pharmacokinetics, pharmacodynamics, maximum tolerated dose (MTD… 
Highly Cited
2004
Highly Cited
2004
PURPOSE This multicenter, open-label, phase II study was undertaken to assess the antitumor activity and safety of the oral… 
Review
2003
Review
2003
Several key growth factors, cytokines, and proto-oncogenes transduce their growth- and differentiation-promoting signals through…