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CGS 26303

Known as: CGS-26303, Phosphonic acid, (((2-(1,1'-biphenyl)-4-yl-1-(1H-tetrazol-5-yl)ethyl)amino)methyl)-, (S)- 
National Institutes of Health

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2 relations

Broader (2)

OrganophosphonatesTetrazoles

Papers overview

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2016
2016
Intrathecal CGS-26303 Pretreatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord.
2007
2007
The peptidase inhibitor CGS‐26303 increases endothelin converting enzyme‐1 expression in endothelial cells through accumulation of big endothelin‐1
CGS‐26303 inhibits endothelin converting enzyme (ECE)‐1 more specifically than phosphoramidon. We have studied the effect of CGS… 
2007
2007
Functional Neuroprotective Effect of CGS 26303, a Dual ECE Inhibitor, on Ischemic-Reperfusion Spinal Cord Injury in Rats
Endothelin-1 (ET-1) has been implicated in many neurological diseases, including subarachnoid hemorrhage (SAH) and cerebral… 
2004
2004
Neuroprotective Effect of CGS 26303, an Endothelin-converting Enzyme Inhibitor, on Transient Middle Cerebral Artery Occlusion in Rats
Endothelin-1 has been shown to aggravate the ischemicreperfusion injury in the neocortex of rats. The purpose of this study was… 
2002
2002
Oral administration of an inhibitor of endothelin-converting enzyme attenuates cerebral vasospasm following experimental subarachnoid haemorrhage in rabbits.
Increasing evidence has implicated endothelin-1 (ET-1), a potent vasoconstrictive peptide, in the pathophysiology of cerebral… 
2000
2000
Effect of CGS 26303, an endothelin-converting enzyme-neutral endopeptidase inhibitor, on nitrofen-induced congenital diaphragmatic hernia in the rat.
BACKGROUND/PURPOSE The pathophysiology of congenital diaphragmatic hernia (CDH) associated with lung hypoplasia and pulmonary… 
1999
1999
Identification of endothelin converting enzyme-1 in human non-pigmented ciliary epithelial cells.
Endothelins (ETs), potent vasoactive peptides, are present in many ocular tissues including the ciliary epithelium where active… 
1999
1999
The role of endothelin in mediating virus-induced changes in endothelinB receptor density in mouse airways.
Emerging evidence supports a mediator role for endothelin (ET)-1 in airway diseases including asthma. Respiratory tract viral… 
1998
1998
Attenuation of experimental subarachnoid hemorrhage-induced cerebral vasospasm by CGS 26303, an endothelin-converting enzyme inhibitor.
The effect of CGS 26303, an endothelin-converting enzyme inhibitor, on the prevention and reversal of cerebral vasospasm was… 
1997
1997
Rat big endothelin-1-induced bronchoconstriction and vasoconstriction in the isolated perfused rat lung: role of endothelin converting enzyme and neutral endopeptidase 24.11
Abstract Treatment of animals with big endothelin-1 (bET) causes pulmonary hypertension and bronchoconstriction, both in vivo and… 
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