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CGP 52608

Known as: CGP-52608, CGP52608 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

ThiazolesThiosemicarbazones

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cellular mechanisms involved in the melatonin inhibition of HT‐29 human colon cancer cell proliferation in culture
Abstract:  The antiproliferative and proapoptotic properties of melatonin in human colon cancer cells in culture were recently… 
Highly Cited
2003
Highly Cited
2003
Melatonin counteracts the inhibitory effect of PGE2 on IL‐2 production in human lymphocytes via its mt1 membrane receptor
It is well known that melatonin plays a fundamental role in human neuro‐immunomodulation. Thus, melatonin regulates the… 
Highly Cited
2001
Highly Cited
2001
Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the murine colonic cancer
The effects of melatonin and the thiazolinidinedione derivative CGP 52608 on apoptosis of Colon 38 cancer cells were investigated… 
Review
2000
Review
2000
Biological Basis and Possible Physiological Implications of Melatonin Receptor- Mediated Signaling in the Rat Epididymis
The mammalian epididymis plays an important role in sperm maturation, an important process of male reproduction. Specific high… 
Highly Cited
1999
Highly Cited
1999
The oncostatic action of melatonin in an ovarian carcinoma cell line
Abstract: Melatonin is reported to reduce proliferation in many cell types, but the effect is small and the results are… 
1999
1999
Antiproliferative Effects of Melatonin and CGP 52608
The antiproliferative effects of melatonin and CGP 52608, an exogenous ligand for RZR/ROR receptors, are compared in the present… 
Highly Cited
1998
Highly Cited
1998
Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells
Highly Cited
1998
Highly Cited
1998
Specific activation of the nuclear receptors PPARgamma and RORA by the antidiabetic thiazolidinedione BRL 49653 and the antiarthritic thiazolidinedione derivative CGP 52608.
The thiazolidinedione BRL 49653 and the thiazolidinedione derivative CGP 52608 are lead compounds of two pharmacologically… 
1996
1996
CGP 52608‐induced cyst formation in dinoflagellates: Possible involvement of a nuclear receptor for melatonin
Abstract: Melatonin has been shown to regulate gene transcription through RZR/ROR nuclear receptors in mammalian cells… 
Highly Cited
1995
Highly Cited
1995
Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand.
Many important physiological functions are controlled by hormones via binding and activating members of the nuclear receptor… 
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