Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

CEP-18770

Known as: CEP 18770, Proteasome Inhibitor CEP 18770 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract Delanzomib (CEP-18770), a reversible P2 threonine boronic acid proteasome (β5/β1 subunits) inhibitor that showed… Expand
Is this relevant?
Review
2013
Review
2013
BACKGROUND The safety, pharmacokinetics (PK) and pharmacodynamics of CEP-18770, a new peptide boronic acid proteasome inhibitor… Expand
Is this relevant?
Review
2013
Review
2013
  • Ota Fuchs
  • Cardiovascular & hematological disorders drug…
  • 2013
  • Corpus ID: 36794356
Multiple myeloma (MM) remains an incurable disease, at least for the big majority of patients, in spite of the great progress… Expand
Is this relevant?
2012
2012
Preclinical and clinical studies have shown that proteasome inhibitors (PIs) have anti-MM activity in combination with… Expand
Is this relevant?
Highly Cited
2010
Highly Cited
2010
The anti‐multiple myeloma (MM) efficacy of bortezomib has led to the development of other proteasome inhibitors (PI), including… Expand
Is this relevant?
2010
2010
CEP-18770, [(1R)-1-{[(2S,3R)-3-hydroxy-2-{[(6-phenyl-2-pyridinyl)carbonyl]amino}butanoyl]amino}-3-methylbutyl]boronic acid, is a… Expand
Is this relevant?
2009
2009
Abstract 1840 Poster Board I-866 Introduction: Currently, there is no orally administered proteasome inhibitor (PI) which has… Expand
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Modulating protein ubiquitination via proteasome inhibition represents a promising target for cancer therapy, because of the… Expand
  • table 1
  • table 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The ubiquitin-proteasome pathway plays a central role in regulation of the production and destruction of cellular proteins. These… Expand
  • figure 1
  • table 1
  • table 2
Is this relevant?
2008
2008
Proteasome inhibitors (PI) have been shown to be effective agents for the treatment of multiple myeloma (MM) and enhance the anti… Expand
Is this relevant?