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CEP-11981

Known as: Pan-VEGFR/TIE2 Tyrosine Kinase Inhibitor CEP-11981 
An orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR) and Tie2 receptor tyrosine kinases with potential… Expand
National Institutes of Health

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2015
2015
[과제] 인간 Tie2에 결합하여, 인간 Tie2를 활성화시킴으로써 당뇨병 황반부종, 당뇨병 망막증 또는 중증 하지허혈을 예방 또는 치료하는 항인간 Tie2… Expand
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2014
2014
The balance between endothelial cell survival and death plays a pivotal role in brain remodeling and repair after stroke [1… Expand
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2014
2014
SummaryBackground This phase I study evaluated the pharmacokinetics and pharmacodynamics of CEP-11981, an oral vascular… Expand
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2012
2012
A substantial body of evidence supports the utility of antiangiogenesis inhibitors as a strategy to block or attenuate tumor… Expand
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2009
2009
A hugyholyagrak a masodik leggyakrabban előfordulo urologiai jellegű tumoros megbetegedes. A mai gyakorlatban kezelesenek modjat… Expand
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2005
2005
The degree of angiogenesis in breast cancer has previously been shown to be an indicator of prognosis, and tumor microvasculature… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Angiopoietin (Ang)-1 is an angiogenic growth factor that counteracts the permeability and proinflammatory effects of… Expand
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2003
2003
The degree of angiogenesis in breast cancer has previously been shown to be an indicator of prognosis, and tumor microvasculature… Expand
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2003
2003
Background—Angiopoietin (Ang)–1 is an angiogenic growth factor that counteracts the permeability and proinflammatory effects of… Expand
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2001
2001
Activation of receptor tyrosine kinases by autophosphorylation is one of the most common and critical transformations in signal… Expand
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