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CEM 101
Known as:
CEM-101
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Macrolides
Triazoles
Solithromycin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Solithromycin (CEM-101): A New Fluoroketolide Antibiotic and Its Role in the Treatment of Gonorrhea
A. Mancuso
,
Mona A. Gandhi
,
J. Slish
Journal of pharmacy and practice
2018
Corpus ID: 206575718
Solithromycin is a macrolide antibiotic that has undergone review for the treatment of community-acquired bacterial pneumonia…
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2016
2016
Efficacy of Solithromycin (CEM-101) for Experimental Otitis Media Caused by Nontypeable Haemophilus influenzae and Streptococcus pneumoniae
M. Figueira
,
P. Fernandes
,
S. Pelton
Antimicrobial Agents and Chemotherapy
2016
Corpus ID: 38961082
ABSTRACT Solithromycin (CEM-101) is a “fourth-generation” macrolide, as it has three binding site and is acid stable. The three…
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2011
2011
Synthesis and antibacterial activity of novel 4-aryl-[1,2,3]-triazole containing macrolides.
D. Pereira
,
P. Fernandes
Bioorganic & Medicinal Chemistry Letters
2011
Corpus ID: 1613201
2011
2011
In Vitro and In Vivo Activity of Solithromycin (CEM-101) against Plasmodium Species
S. Wittlin
,
E. Ekland
,
+4 authors
P. Fernandes
Antimicrobial Agents and Chemotherapy
2011
Corpus ID: 20677957
ABSTRACT With the emergence of Plasmodium falciparum infections exhibiting increased parasite clearance times in response to…
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2010
2010
Comparison of CEM-101 Metabolism in Mice, Rats, Monkeys and Humans
D. Pereira
2010
Corpus ID: 98071550
Results 2010 ICAAC, Boston, MA David Pereira, Ph.D. 6340 Quadrangle Drive, Suite 100 Chapel Hill, North Carolina 27517 dpereira…
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2009
2009
MIC Quality Control Guidelines and Disk Diffusion Test Optimization for CEM-101, a Novel Fluoroketolide
Ronald N. Jones
,
J. E. Ross
,
P. Rhomberg
Journal of Clinical Microbiology
2009
Corpus ID: 35636293
ABSTRACT The development of diagnostic susceptibility tests for CEM-101, a new fluoroketolide, was addressed by structured…
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2008
2008
Binding and Action of CEM-101, A New Macrolide/Ketolide in Development for Treating Infections with Macrolide-Resistant and Macrolide-Susceptible Bacteria
Beatriz Llano-Sotelo
2008
Corpus ID: 88116528
CEM-101 displayed a tight binding to the ribosome from sensitive Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria…
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2008
2008
Antimicrobial Characterization of CEM-101: PAE, Bactericidal Activity and Combinations
Ronald N. Jones
2008
Corpus ID: 87858376
MBC determinations for CEM-101, telithromycin (TEL) and clarithromycin (CLA) used CLSI methods for 40 strains (6 species groups…
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2008
2008
Antimicrobial Characterization of CEM-101 Activity Against 331 Respiratory Tract Pathogens Including Multidrug-Resistant Pneumococcal Serogroup 19A (MDR-19A) Isolates
Ronald N. Jones
2008
Corpus ID: 87531920
A worldwide sample of organisms included S. pneumoniae (SPN; 168, 59.3% erythromycin [ERY]-R and 18 MDR-19A strains), M…
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2008
2008
Evaluation of CEM-101, a Novel Macrolide, in Murine Infection Models
Timothy M. Murphy
2008
Corpus ID: 87536808
Efficacy was evaluated in several infection models. CD-1 female mice were infected IP; CEM-101 or comparators were administered…
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