CDX2 Protein, human

Known as: Caudal-Type Homeobox Protein 2, caudal type homeo box transcription factor 2 protein, human, Caudal-Type Homeo Box Transcription Factor 2 
Homeobox protein CDX-2 (313 aa, ~34 kDa) is encoded by the human CDX2 gene. This protein is involved in transcription and intestinal morphogenesis.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Background The identification of high-risk stage II colon cancers is key to the selection of patients who require adjuvant… (More)
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
The mouse blastocyst and stem cells derived from its tissue lineages provide a unique genetic system for examining the… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Inactivation of Cdx2 leads to preimplantation embryonic lethality. Rescue of the implantation defect by tetraploid fusion… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The histologic diagnosis of Barrett's esophagus requires the presence of goblet cells, but this finding may not be the earliest… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The roles of CDX2 and CDX1 homeobox genes during gastric carcinogenesis remain poorly defined. We have studied the expression of… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Mouse Cdx and Hox genes presumably evolved from genes on a common ancestor cluster involved in anteroposterior patterning… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS The intestine-specific transcription factors Cdx1 and Cdx2 are candidate genes for directing intestinal… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The homeobox gene Cdx2, a homologue of the Drosophila gene caudal, has been implicated in the control of cell differentiation in… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
In Drosophila, disturbing the expression of the homeobox gene caudal causes a severe disruption in body segmentation and global… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Defining the molecular mechanisms involved in cancer formation and progression is still a major challenge in colorectal-cancer… (More)
Is this relevant?