CDP323
National Institutes of Health
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ABSTRACT Introduction: The α4β7 integrin is heterodimeric cell surface receptors expressed on most leukocytes. Mucosal addressing…
We identified the enzyme(s) involved in the hydrolysis of the ethyl ester prodrug CDP323 (C28H29BrN403) and characterized its…
Background Lymphocyte inhibition by antagonism of α4 integrins is a validated therapeutic approach for relapsing multiple…
We identified the enzyme(s) involved in the hydrolysis of the ethyl ester prodrug CDP323 (C28H29BrN403) and characterized its…