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CDKAL1 gene

Known as: CDKAL1, CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1-LIKE 1, FLJ20342 
National Institutes of Health

Related topics

Related topics

1 relation
CDK5RAP1 gene

Papers overview

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2015
2015
The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes
Metabolic syndrome (MetS) is prevalent in type 2 diabetes (T2D) patients. The comorbidity of MetS and T2D increases the risk of… 
Highly Cited
2013
Highly Cited
2013
Clinical and genetic risk factors for type 2 diabetes at early or late post partum after gestational diabetes mellitus.
CONTEXT Women with a history of gestational diabetes mellitus (GDM) are at increased risk of type 2 diabetes (T2DM). However, the… 
Review
2011
Review
2011
Meta‐analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis
Background: Both ulcerative colitis (UC) and Crohn's disease (CD) have a complex etiology involving multiple genetic and… 
Highly Cited
2010
Highly Cited
2010
Deletion of CDKAL1 Affects Mitochondrial ATP Generation and First-Phase Insulin Exocytosis
Background A variant of the CDKAL1 gene was reported to be associated with type 2 diabetes and reduced insulin release in humans… 
Highly Cited
2010
Highly Cited
2010
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
Aims/hypothesisThe fetal insulin hypothesis suggests that variation in the fetal genotype influencing insulin secretion or action… 
Review
2009
Review
2009
Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European Ancestry
Context Individual genetic polymorphisms are weakly associated with type 2 diabetes. It is unclear whether genetic information… 
Highly Cited
2009
Highly Cited
2009
Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22.
Predisposition to psoriasis is known to be affected by genetic variation in HLA-C, IL12B, and IL23R, and although other psoriasis… 
Highly Cited
2009
Highly Cited
2009
Examination of Type 2 Diabetes Loci Implicates CDKAL1 as a Birth Weight Gene
OBJECTIVE A number of studies have found that reduced birth weight is associated with type 2 diabetes later in life; however, the… 
Highly Cited
2008
Highly Cited
2008
Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps
Aims/hypothesisGenome-wide association studies have recently identified novel type 2 diabetes susceptibility gene regions. We… 
Highly Cited
2008
Highly Cited
2008
Post Genome-Wide Association Studies of Novel Genes Associated with Type 2 Diabetes Show Gene-Gene Interaction and High Predictive Value
Background Recently, several Genome Wide Association (GWA) studies in populations of European descent have identified and… 
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