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CDK5RAP3 gene

Known as: C53, LXXLL/LEUCINE ZIPPER-CONTAINING ARF-BINDING PROTEIN, OK/SW-cl.114 
This gene plays a role in cellular proliferation.
National Institutes of Health

Related topics

Related topics

4 relations
CDK5RAP3 protein, humanCell Cycle ControlCell Proliferation Regulatory Process

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CDK5RAP3 wt Allele

Papers overview

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2019
2019
Overexpression of IC53d promotes the proliferation of gastric cancer cells by activating the AKT/GSK3β/cyclin D1 signaling pathway
Cyclin-dependent kinase 5 regulatory subunit- associated protein 3 (CDK5RAP3 or C53) is involved in the development of various… 
2017
2017
LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro
ABSTRACT The phosphatase Wip1 attenuates the DNA damage response (DDR) by removing phosphorylation marks from a number of DDR… 
2015
2015
Tumor Suppressor Lzap Suppresses Wnt/β-Catenin Signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of Glycogen Synthase Kinase 3*
Background: Lzap is a novel tumor suppressor. Results: Elimination of Lzap in fish embryos or in a human tongue carcinoma cell… 
2013
2013
O73 Étude par protéomique quantitative de la réponse compensatoire des îlots pancréatiques face à la résistance à l’insuline
2012
2012
Expression of TIP-1 Confers Radioresistance of Malignant Glioma Cells
Background Malignant gliomas represent one group of tumors that poorly respond to ionizing radiation (IR) alone or combined with… 
2011
2011
LZAP Inhibits p38 MAPK (p38) Phosphorylation and Activity by Facilitating p38 Association with the Wild-Type p53 Induced Phosphatase 1 (WIP1)
LZAP (Cdk5rap3, C53) is a putative tumor suppressor that inhibits RelA, Chk1 and Chk2 and activates p53. LZAP is lost in a… 
2011
2011
Antibody against the IC53 gene in patient with heart failure
Objective:To explore whether antibody against IC53 gene is related to CHF induced by different cardiac diseases.Method:①188… 
2010
2010
Abstract 3063: Novel putative tumor suppressor LZAP binds and regulates Wip1
Our group has shown that LZAP is lost in ∼30% of head and neck squamous cell carcinomas and that inhibition of LZAP expression is… 
2003
2003
Cloning and characterization of human IC53-2, a novel CDK5 activator binding protein
ABSTRACTWe have identified IC53-2, a human homologue of the rat C53 gene from a human placenta cDNA library (GeneBank Accession… 
2002
2002
A novel gene IC53 stimulates ECV304 cell proliferation and is upregulated in failing heart.
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