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CDK16 gene

Known as: PCTGAIRE, serine/threonine-protein kinase, Cyclin-Dependent Kinase 16 Homolog Gene 
This gene is involved in cell cycle regulation and signal transduction.
National Institutes of Health

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CDK16 wt Allele
Cell Cycle ControlPCTK1 protein, humanPhosphorylationProtein-Serine-Threonine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer
Abstract This study reports the application of inverse virtual screening (iVS) methodologies to identify cellular proteins as… 
2017
2017
Inhibition of miRNA-21 attenuates the proliferation and metastasis of human osteosarcoma by upregulating PTEN.
The present study aimed to investigate the expression of micro (mi)RNA-21 in osteosarcoma cells, and its role in inhibiting the… 
Highly Cited
2016
Highly Cited
2016
The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873
Emerging evidences suggest that necrosis is programmed and is one of the main forms of cell death in the pathological process in… 
2016
2016
miR-33a is downregulated in melanoma cells and modulates cell proliferation by targeting PCTAIRE1
MicroRNA-33a (miR-33a) was previously identified as a lipid regulator that controls the cellular balance between cholesterol and… 
2015
2015
Upregulated CDK16 Expression in Serous Epithelial Ovarian Cancer Cells
Background As CDK-16 has been shown to be upregulated in several transformed cancer lines, we hypothesized that the cyclin… 
2013
2013
ENSA expression correlates with attenuated tumor propagation in liver cancer.
2004
2004
Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain.
Highly Cited
1996
Highly Cited
1996
Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase.
In addition to the previously identified Drosophila cdc2 and cdc2c genes, we have identified four additional cdc2-related genes… 
1995
1995
Physical linkage of the cdc2-related gene (PCTK1) and the ubiquitin-activating enzyme E1 gene (UBE1) on human Xp11.3.
PCTAIRE-1 is a cdc2-related protein kinase of unknown function. The gene (PCTK1) has been mapped to chromosome Xp. In this study… 
1994
1994
Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes.
Recent studies on the molecular mechanisms controlling the mammalian cell cycle have disclosed a large family of cdc2-related… 
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