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CDK16 gene

Known as: PCTGAIRE, serine/threonine-protein kinase, Cyclin-Dependent Kinase 16 Homolog Gene 
This gene is involved in cell cycle regulation and signal transduction.
National Institutes of Health

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CDK16 wt Allele
Cell Cycle ControlPCTK1 protein, humanPhosphorylationProtein-Serine-Threonine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
New tricks of an old autophagy regulator: AMPK-dependent regulation of autophagy through CCNY (cyclin Y)-CDK16
ABSTRACT AMPK is one of the main regulators of energy homeostasis in the cell, achieving this role in part by upregulating… 
2019
2019
Issue Information
Mesenchymal stem cells in acute kidney injury TRPV4 regulates TGFβ1-induced epithelial-mesenchymal transition Age-related… 
2018
2018
iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer
Abstract This study reports the application of inverse virtual screening (iVS) methodologies to identify cellular proteins as… 
2018
2018
Connecting immune deficiency and inflammation
RIPK1 mutations result in immune deficiency and autoinflammation in humans Advances in genomic technologies have revealed the… 
2016
2016
miR-33a is downregulated in melanoma cells and modulates cell proliferation by targeting PCTAIRE1
MicroRNA-33a (miR-33a) was previously identified as a lipid regulator that controls the cellular balance between cholesterol and… 
2015
2015
Upregulated CDK16 Expression in Serous Epithelial Ovarian Cancer Cells
Background As CDK-16 has been shown to be upregulated in several transformed cancer lines, we hypothesized that the cyclin… 
1998
1998
UHX1 and PCTK1: precise characterisation and localisation within a gene-rich region in Xp11.23 and evaluation as candidate genes for retinal diseases mapped to Xp21.1–p11.2
The gene for ubiquitin hydrolase on the X chromosome (UHX1), cloned and mapped to Xp21.2–p11.2, is a candidate gene for retinal… 
Highly Cited
1996
Highly Cited
1996
Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase.
In addition to the previously identified Drosophila cdc2 and cdc2c genes, we have identified four additional cdc2-related genes… 
1995
1995
Physical linkage of the cdc2-related gene (PCTK1) and the ubiquitin-activating enzyme E1 gene (UBE1) on human Xp11.3.
PCTAIRE-1 is a cdc2-related protein kinase of unknown function. The gene (PCTK1) has been mapped to chromosome Xp. In this study… 
1994
1994
Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes.
Recent studies on the molecular mechanisms controlling the mammalian cell cycle have disclosed a large family of cdc2-related… 
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