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CD82 protein, human

Known as: KAI1 Protein, R2 Leukocyte Surface Antigen, R2 leukocyte antigen, human 
CD82 antigen (267 aa, ~30 kDa) is encoded by the human CD82 gene. This protein plays a role in the T-cell receptor signaling pathway.
National Institutes of Health

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Related topics

16 relations
CD82 geneCD82 wt AlleleCell AdhesionClusters of differentiation

Broader (1)

Lymphocyte antigen CD82

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Overexpression of KAI1/CD82 suppresses in vitro cell growth, migration, invasion and xenograft growth in oral cancer
KAI1/CD82 is a metastatic suppressor gene in human prostate cancer and several other types of cancer in humans. The present study… 
2007
2007
An alternatively spliced KAI1 mRNA is expressed at low levels in human bladder cancers and bladder cancer cell lines and is not associated with invasive behaviour.
Levels of the KAI1 metastasis suppressor are reduced in advanced stages of many human cancers, leading to the loss of KAI1… 
2005
2005
KAI1 inhibits anchorage-dependent and -independent pancreatic cancer cell growth.
Decreased expression of the tumor suppressor gene, KAI1, is associated with metastasis formation in pancreatic cancer. The aim of… 
2005
2005
Prognostic values of KAI1 and survivin expression in an infiltrating ductal carcinoma of the breast
Aims: To investigate KAI1 and survivin expression in infiltrating ductal carcinomas, and to evaluate the relationship between… 
2003
2003
Downregulation of KAI1 mRNA in localised prostate cancer and its bony metastases does not correlate with p53 overexpression
Recent data have proposed that transcription of the KAI1 metastasis suppressor gene is directly mediated by p53 and that loss of… 
2003
2003
Identification of regulatory regions within the KAI1 promoter: a role for binding of AP1, AP2 and p53.
2003
2003
Effects of KAI1/CD82 on biological behavior of human colorectal carcinoma cell line.
AIM To investigate the effects of KAI1/CD82 on biological behavior of colorectal carcinoma cells. METHODS KAI1 cDNA was… 
2002
2002
High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis.
PURPOSE KAI1 was originally identified in prostate cancer as a metastasis suppressor gene. Recent studies have shown a frequent… 
2000
2000
The impact of expression of the metastasis suppressor protein KAI1 on prognosis in invasive squamous cell cervical cancer.
OBJECTIVES Loss of KAI1 protein is a frequent event in various types of cancer and has been reported to be associated with… 
1998
1998
KAI1 is unchanged in metastatic and nonmetastatic esophageal and gastric cancers.
Down-regulation of KAI1 mRNA expression has been shown to be associated with the formation of metastases or disease progression… 
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