CD59 protein, human

Known as: 20 kDa homologous restriction factor, human, MEM43 Antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) protein, human 
CD59 glycoprotein (128 aa, ~14 kDa) is encoded by the human CD59 gene. This protein is involved in the inhibition of the assembly of the membrane… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
05101519892017

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE To evaluate and compare the glaucoma discrimination ability of macular inner retinal layer (MIRL) thickness with that of… (More)
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2000
2000
PURPOSE To explore the role of the complement system and complement regulatory proteins in an immune-privileged organ, the eye… (More)
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2000
2000
Hepatic parenchymal cells respond in many different ways to acute-phase cytokines. Some responses may protect against damage by… (More)
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Highly Cited
1997
Highly Cited
1997
We characterize a line of transgenic pigs that express the human complement-regulatory proteins human CD59 and human decay… (More)
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Highly Cited
1996
Highly Cited
1996
Normal human tissues express membrane-associated complement inhibitory proteins that protect these tissues from damage by… (More)
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1994
1994
The kidney is an organ where complement-mediated tissue injuries take place by various stimuli. To assess how the kidney is… (More)
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1992
1992
The complement (C) regulatory proteins decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46), which… (More)
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1991
1991
When incubated in acidified serum, the erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH) are hemolyzed through activation… (More)
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1991
1991
Protectin (CD59) is a recently discovered 18-20 kDa glycoprotein that effectively inhibits lysis by the membrane attack complex… (More)
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Highly Cited
1990
Highly Cited
1990
Human cells are relatively resistant to lysis by the homologous complement system. Here we describe the mechanism of action of a… (More)
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