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CD209 gene

Known as: DENDRITIC CELL-SPECIFIC ICAM3-GRABBING NONINTEGRIN, DC-SIGN1, CD209 ANTIGEN 
This gene plays a role in the regulation of host defense responses and mediates pathogen-binding properties.
National Institutes of Health

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Related topics

9 relations
Acquired Immunodeficiency SyndromeAntigen PresentationCD209 protein, humanCell Adhesion

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CD209 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Immune cell subset differentiation and tissue inflammation
Immune cells were traditionally considered as major pro-inflammatory contributors. Recent advances in molecular immunology prove… 
Highly Cited
2013
Highly Cited
2013
Cancer‐associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients
Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its… 
Highly Cited
2012
Highly Cited
2012
Orientia tsutsugamushi in Human Scrub Typhus Eschars Shows Tropism for Dendritic Cells and Monocytes Rather than Endothelium
Scrub typhus is a common and underdiagnosed cause of febrile illness in Southeast Asia, caused by infection with Orientia… 
Highly Cited
2011
Highly Cited
2011
DC-SIGN (CD209) Promoter −336 A/G Polymorphism Is Associated with Dengue Hemorrhagic Fever and Correlated to DC-SIGN Expression and Immune Augmentation
Background The C-type lectin DC-SIGN (CD209) is known to be the major dengue receptor on human dendritic cells, and a single… 
Review
2009
Review
2009
Innate signaling by the C-type lectin DC-SIGN dictates immune responses
Effective immune responses depend on the recognition of pathogens by dendritic cells (DCs) through pattern recognition receptors… 
Highly Cited
2009
Highly Cited
2009
A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis
The C-type lectin dendritic cell−specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN) mediates the innate… 
Highly Cited
2009
Highly Cited
2009
The DC-SIGN of Zebrafish: Insights into the Existence of a CD209 Homologue in a Lower Vertebrate and Its Involvement in Adaptive Immunity1
Dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN/CD209) has become hot topic in recent studies because of its… 
Highly Cited
2006
Highly Cited
2006
Dectin-2 Is a Pattern Recognition Receptor for Fungi That Couples with the Fc Receptor γ Chain to Induce Innate Immune Responses*
Antigen presenting cells recognize pathogens via pattern recognition receptors (PRR), which upon ligation transduce intracellular… 
Review
2006
Review
2006
Glycans modulate immune responses in helminth infections and allergy.
Infections of humans and animals by parasitic helminths share key features with atopic diseases, such as allergic asthma. Both… 
Highly Cited
2002
Highly Cited
2002
A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation.
In vaccine development, a major objective is to induce strong, specific T cell responses. This might be obtained by targeting… 
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