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CCR8 protein, human

Known as: CY6, Chemokine (C-C) Receptor 8, TER1 protein, human 
C-C chemokine receptor type 8 (355 aa, ~41 kDa) is encoded by the human CCR8 gene. This protein is involved in chemokine signaling.
National Institutes of Health

Related topics

Related topics

23 relations
ApoptosisCCR8 geneCCR8 wt AlleleCCRL2 protein, human

Broader (1)

Receptors, CCR8

Papers overview

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Highly Cited
2016
Highly Cited
2016
Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer.
Review
2016
Review
2016
Atypical chemokine receptors in cancer: friends or foes?
The chemokine system is a fundamental component of cancer‐related inflammation involved in all stages of cancer development. It… 
Highly Cited
2008
Highly Cited
2008
Identification and characterization of the Schizosaccharomyces pombe TER1 telomerase RNA
Although the catalytic subunit of the Schizosaccharomyces pombe telomerase holoenzyme was identified over ten years ago, the… 
Highly Cited
2006
Highly Cited
2006
CCR8 Expression Identifies CD4 Memory T Cells Enriched for FOXP3+ Regulatory and Th2 Effector Lymphocytes
CD4+ Th2 cells are important regulators of allergic inflammation. CCR8 is thought to play a role in Th2-mediated responses… 
Highly Cited
2005
Highly Cited
2005
CCR8 Is Expressed by Antigen-Elicited, IL-10-Producing CD4+CD25+ T Cells, Which Regulate Th2-Mediated Granuloma Formation in Mice1
CCR8 was initially described as a Th2 cell-restricted receptor, but this has not been fully tested in vivo. The present study… 
Highly Cited
2004
Highly Cited
2004
CCL16 activates an angiogenic program in vascular endothelial cells.
Besides regulating leukocyte trafficking in normal and injured tissues, several chemokines may positively or negatively regulate… 
Highly Cited
2003
Highly Cited
2003
Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions.
Highly Cited
2001
Highly Cited
2001
Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice
Chemokine receptors transduce signals important for the function and trafficking of leukocytes. Recently, it has been shown that… 
Highly Cited
1999
Highly Cited
1999
HHV8-encoded vMIP-I Selectively Engages Chemokine Receptor CCR8
Uncertainty regarding viral chemokine function is mirrored by an incomplete knowledge of host chemokine receptor usage by the… 
Highly Cited
1997
Highly Cited
1997
Identification of CCR8, the Receptor for the Human CC Chemokine I-309*
The nucleotide sequence for a putative chemokine receptor, termed TER1, ChemR1, or CKR-L1, was recently obtained by a polymerase… 
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