CC-885

 

Topic mentions per year

Topic mentions per year

2016-2018
01220162018

Papers overview

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2018
2018
We previously disclosed the identification of cereblon modulator 3 (CC-885), with potent antitumor activity mediated through the… (More)
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2017
2017
Immunomodulatory drugs (IMiDs), today also known as cereblon (CRBN) binding drugs, are therapeutically important anti-cancer and… (More)
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Review
2017
Review
2017
Immunomodulatory drugs (IMiDs) are a new class of anticancer compounds that are derived from thalidomide. Lenalidomide and… (More)
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2016
2016
Immunomodulatory drugs bind to cereblon (CRBN) to confer differentiated substrate specificity on the CRL4(CRBN) E3 ubiquitin… (More)
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2016
2016
  • Cancer discovery
  • 2016
A common motif likely promotes binding of substrates, including GSPT1, to cereblon. 
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