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CBR 703
Known as:
CBR-703
, CBR703
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Amidines
Hydroxylamines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Y. Feng
,
David Degen
,
+9 authors
R. Ebright
Structure
2015
Corpus ID: 4959752
CBR hydroxamidines are small-molecule inhibitors of bacterial RNA polymerase (RNAP) discovered through high-throughput screening…
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2014
2014
CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase
A. Malinen
,
Monali NandyMazumdar
,
+4 authors
G. Belogurov
Nature communications
2014
Corpus ID: 16943462
Bacterial RNA polymerase (RNAP) is a validated target for antibacterial drugs. CBR703 series antimicrobials allosterically…
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2014
2014
New Insights into the Bacterial RNA Polymerase Inhibitor CBR703 as a Starting Point for Optimization as an Anti-Infective Agent
W. Zhu
,
Jörg Haupenthal
,
M. Groh
,
M. Fountain
,
R. Hartmann
Antimicrobial Agents and Chemotherapy
2014
Corpus ID: 63055
ABSTRACT CBR703 was reported to inhibit bacterial RNA polymerase (RNAP) and biofilm formation, considering it to be a good…
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2007
2007
In Vitro Activities of Different Inhibitors of Bacterial Transcription against Staphylococcus epidermidis Biofilm
Philippe Villain-Guillot
,
M. Gualtiéri
,
L. Bastide
,
Jean-Paul Léonetti
Antimicrobial Agents and Chemotherapy
2007
Corpus ID: 24889650
ABSTRACT Staphylococcus epidermidis is a major cause of nosocomial infections because of its ability to form biofilms on the…
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Highly Cited
2003
Highly Cited
2003
A New Class of Bacterial RNA Polymerase Inhibitor Affects Nucleotide Addition
I. Artsimovitch
,
Clement Chu
,
A. S. Lynch
,
R. Landick
Science
2003
Corpus ID: 27587353
RNA polymerase (RNAP) is the central enzyme of gene expression. Despite availability of crystal structures, details of its…
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