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CBL wt Allele

Known as: CBL2, Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence wt Allele, C-CBL 
Human CBL wild-type allele is located in the vicinity of 11q23.3 and is approximately 102 kb in length. This allele, which encodes E3 ubiquitin… 
National Institutes of Health

Related topics

Related topics

7 relations
11q23.3B-Cell LymphomasCBL geneHematopoiesis

Papers overview

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Highly Cited
2012
Highly Cited
2012
S-acylation-dependent association of the calcium sensor CBL2 with the vacuolar membrane is essential for proper abscisic acid responses
Calcineurin B-like (CBL) proteins contribute to decoding calcium signals by interacting with CBL-interacting protein kinases… 
Highly Cited
2004
Highly Cited
2004
The c‐Cbl/CD2AP complex regulates VEGF‐induced endocytosis and degradation of Flt‐1 (VEGFR‐1)
Vascular endothelial growth factor (VEGF) and its receptors are key regulators of angiogenesis and are potential targets in… 
Highly Cited
2001
Highly Cited
2001
RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation.
Highly Cited
1999
Highly Cited
1999
cbl-b inhibits epidermal growth factor receptor signaling
The role of cbl-b in signaling by the epidermal growth factor receptor (EGFR) was studied and compared with c-cbl. We demonstrate… 
Highly Cited
1996
Highly Cited
1996
Anticipation in familial leukemia.
Anticipation refers to worsening severity or earlier age at onset with each generation for an inherited disease and primarily has… 
Highly Cited
1996
Highly Cited
1996
Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes
Accumulating data show that the tyrosine protein kinase Zap-70 plays an essential role in T cell receptor-mediated signal… 
Highly Cited
1995
Highly Cited
1995
Tyrosine Phosphorylation and Translocation of the c-Cbl Protein after Activation of Tyrosine Kinase Signaling Pathways (*)
The c-cbl protooncogene product (c-Cbl) is a 120-kDa protein that has been shown to bind to the Src homology 3 domains of various… 
Highly Cited
1995
Highly Cited
1995
Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2
The fragile site FRA11B has been localized to the p(CCG)n repeat of the CBL2 proto-oncogene. A proportion of Jacobsen (11q… 
1994
1994
Intrinsic radiosensitivity of adult and cord blood lymphocytes as determined by the micronucleus assay.
Highly Cited
1994
Highly Cited
1994
Physical linkage of the fragile site FRA11B and a Jacobsen syndrome chromosome deletion breakpoint in 11q23.3.
Autosomal fragile sites, unlike their X-linked counterparts, are not known to be associated with disease. However, one case… 
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