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CBL Protein

Known as: CBL, CBL Gene Product, CBL2 Gene Product 
The cellular homologue of v-cbl, CBL protein is expressed in a range of hemopoietic lineages. Malignancies are associated with translocations of the… 
National Institutes of Health

Related topics

Related topics

8 relations
CBL geneCell NucleusHematopoiesisHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Effects of Temporal Discretization on Turbulence Statistics and Spectra in Numerically Simulated Convective Boundary Layers
Six state-of-the-art large-eddy simulation codes were compared in Fedorovich et al. (Preprints, 16th American Meteorological… 
Review
2013
Review
2013
Cbl‐family proteins as regulators of cytoskeleton‐dependent phenomena
Although the role of Cbl‐family proteins as key cellular regulators has been established, phenomena regulated in a Cbl‐dependent… 
2013
2013
Abstract 1036: Cbl-independent degradation of Met: Ways to avoid agonism of bivalent Met targeting antibody.
The Met receptor tyrosine kinase, found to be constitutively activated in many tumors, has become a leading target for cancer… 
2012
2012
CBL mutations do not frequently occur in paediatric acute myeloid leukaemia
RAS‐pathway mutations, causing a proliferative advantage, occur in acute myeloid leukaemia (AML) and MLL‐rearranged leukaemia… 
2004
2004
Biochemical Basis for the Requirement of Kinase Activity for Cbl-dependent Ubiquitinylation and Degradation of a Target Tyrosine Kinase*
Members of the Cbl family of ubiquitin ligases have emerged as crucial negative regulators of tyrosine kinase signaling. These… 
2002
2002
Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells
CBL and the related CBL-B protein are two members of a family of RING finger type ubiquitin E3 ligases that are believed to… 
2002
2002
An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn.
The Cbl family of ubiquitin ligases function as negative regulators of activated receptor tyrosine kinases by facilitating their… 
2001
2001
Atmospheric convergence diabatically generated in the CBL over a mountainous peninsula
The mesoscale atmospheric flow is investigated that is diabatically forced by the diurnal warming in the convective boundary… 
2000
2000
All-trans-retinoic acid induces tyrosine phosphorylation of the CrkL adapter in acute promyelocytic leukemia cells.
1999
1999
CBL: Crossing the Boundaries.
This paper offers a few examples of the ease with which science, mathematics and technology may converge. Using the CBL… 
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