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CASP3 wt Allele
Known as:
Caspase 3, Apoptosis-Related Cysteine Peptidase wt Allele
, PARP Cleavage Protease Gene
, Cysteine Protease CPP32 Gene
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Human CASP3 wild-type allele is located within 4q34 and is approximately 22 kb in length. This allele, which encodes caspase-3 protein, is involved…
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National Institutes of Health
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Related topics
Related topics
15 relations
4q34
Alzheimer's Disease
Alzheimer's Disease Pathway KEGG
Apoptosis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis
Huiyuan Zhang
,
Haiyan S. Li
,
+16 authors
S. Watowich
Proceedings of the National Academy of Sciences
2018
Corpus ID: 3792936
Significance Inflammation degrades hematopoietic stem and progenitor (HSPC) function, leading to myeloid-skewing and bone marrow…
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2017
2017
Reduced Erg Dosage Impairs Survival of Hematopoietic Stem and Progenitor Cells
Ying Xie
,
M. L. Koch
,
+7 authors
Zhe Li
Stem cells
2017
Corpus ID: 4478139
ERG, an ETS family transcription factor frequently overexpressed in human leukemia, has been implicated as a key regulator of…
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2017
2017
Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice
Shin-Young Park
,
A. Mattè
,
+4 authors
L. Silberstein
2017
Corpus ID: 202806254
Sickle cell disease is a worldwide distributed hereditary red cell disorder, caused by pathologic hemoglobin S (HbS). The main…
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2015
2015
The Role of Jarid2 in Leukemic Transformation of Chronic Myeloid Neoplasms
Hamza Celik
,
A. Martens
,
+4 authors
G. Challen
2015
Corpus ID: 208435681
Despite the increasing use of targeted therapies, a subset of patients with myeloproliferative neoplasms (MPN) transform to…
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2007
2007
Expression of c‐kit and Sca‐1 and their relationship with multidrug resistance protein 1 in mouse bone marrow mononuclear cells
F. Kyle-Cezar
,
J. Echevarria-Lima
,
R. Goldenberg
,
V. Rumjanek
Immunology
2007
Corpus ID: 19443611
P‐glycoprotein (Pgp) and multidrug resistance protein 1 (MRP1) are members of the ATP‐binding cassette (ABC) family of…
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2004
2004
Hematopoietic-repopulating defects from STAT5-deficient bone marrow are not fully accounted for by loss of thrombopoietin responsiveness.
H. Bradley
,
C. Couldrey
,
K. D. Bunting
Blood
2004
Corpus ID: 9714208
Signal transducer and activator of transcription-5 (STAT5) plays an important role in repopulating activity of hematopoietic stem…
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2003
2003
免疫磁性分选骨髓干细胞亚群Thy-1^low Lin^- Sca-1^+
何劲松
,
陈积圣
,
闵军
,
魏菁
,
蔡云峰
,
邵静
2003
Corpus ID: 179899214
目的采用免疫磁性细胞分选系统(MACS)分离纯化骨髓干细胞亚群Thy-1lowLin Sca-1+ .方法收集小鼠股骨骨髓细胞,用MACS系统,通过三步分选步骤选择Thy-1low Sca-1+细胞,去除Lin+细胞,得骨髓干细胞亚群Thy-1lowLin…
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Highly Cited
1998
Highly Cited
1998
Characterization of a Population of Cells in the Bone Marrow that Phenotypically Mimics Hematopoietic Stem Cells: Resting Stem Cells or Mystery Population?
T. Randall
,
I. Weissman
Stem cells
1998
Corpus ID: 32941639
We have identified a population of cells in murine bone marrow that has many of the phenotypic characteristics attributed to…
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Highly Cited
1996
Highly Cited
1996
Partially differentiated ex vivo expanded cells accelerate hematologic recovery in myeloablated mice transplanted with highly enriched long-term repopulating stem cells.
S. Szilvassy
,
K. Weller
,
B. Chen
,
C. Juttner
,
A. Tsukamoto
,
R. Hoffman
Blood
1996
Corpus ID: 2760215
The ability of an infusion of ex vivo expanded hematopoietic cells to ameliorate cytopenia following transplantation of…
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1994
1994
The development of natural killer (NK) cells from Thy-1loLin-Sca-1+ stem cells: acquisition by NK cells in vivo of the homing receptor MEL-14 and the integrin Mac-1.
S. Miller
Immunobiology
1994
Corpus ID: 20779856
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