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CASP3 wt Allele

Known as: Caspase 3, Apoptosis-Related Cysteine Peptidase wt Allele, PARP Cleavage Protease Gene, Cysteine Protease CPP32 Gene 
Human CASP3 wild-type allele is located within 4q34 and is approximately 22 kb in length. This allele, which encodes caspase-3 protein, is involved… Expand
National Institutes of Health

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Related topics

15 relations
4q34Alzheimer's DiseaseAlzheimer's Disease Pathway KEGGApoptosis
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Papers overview

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2018
2018
Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.
Blood cell formation must be appropriately maintained throughout life to provide robust immune function, hemostasis, and oxygen… Expand
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2017
2017
Reduced Erg Dosage Impairs Survival of Hematopoietic Stem and Progenitor Cells.
ERG, an ETS family transcription factor frequently overexpressed in human leukemia, has been implicated as a key regulator of… Expand
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2017
2017
Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice
Sickle cell disease is a worldwide distributed hereditary red cell disorder, caused by pathologic hemoglobin S (HbS). The main… Expand
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2015
2015
The Role of Jarid2 in Leukemic Transformation of Chronic Myeloid Neoplasms
Despite the increasing use of targeted therapies, a subset of patients with myeloproliferative neoplasms (MPN) transform to… Expand
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2007
2007
Expression of c-kit and Sca-1 and their relationship with multidrug resistance protein 1 in mouse bone marrow mononuclear cells.
P-glycoprotein (Pgp) and multidrug resistance protein 1 (MRP1) are members of the ATP-binding cassette (ABC) family of… Expand
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2004
2004
Hematopoietic-repopulating defects from STAT5-deficient bone marrow are not fully accounted for by loss of thrombopoietin responsiveness.
Signal transducer and activator of transcription-5 (STAT5) plays an important role in repopulating activity of hematopoietic stem… Expand
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2003
2003
免疫磁性分选骨髓干细胞亚群Thy-1^low Lin^- Sca-1^＋
目的采用免疫磁性细胞分选系统(MACS)分离纯化骨髓干细胞亚群Thy-1lowLin Sca-1+ .方法收集小鼠股骨骨髓细胞,用MACS系统,通过三步分选步骤选择Thy-1low Sca-1+细胞,去除Lin+细胞,得骨髓干细胞亚群Thy-1lowLin… Expand
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1998
1998
Characterization of a population of cells in the bone marrow that phenotypically mimics hematopoietic stem cells: resting stem cells or mystery population?
We have identified a population of cells in murine bone marrow that has many of the phenotypic characteristics attributed to… Expand
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1996
1996
Partially differentiated ex vivo expanded cells accelerate hematologic recovery in myeloablated mice transplanted with highly enriched long-term repopulating stem cells.
The ability of an infusion of ex vivo expanded hematopoietic cells to ameliorate cytopenia following transplantation of… Expand
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1994
1994
The development of natural killer (NK) cells from Thy-1loLin-Sca-1+ stem cells: acquisition by NK cells in vivo of the homing receptor MEL-14 and the integrin Mac-1.
The present study aimed to follow the development of natural killer (NK) cells in lethally irradiated BA mice reconstituted with… Expand
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