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CAP-Gly Domain-Containing Linker Protein 1, human

Known as: Reed-Sternberg Microtubule-Associated Protein, CAP-Gly Domain-Containing Linker Protein 1, Cytoplasmic Linker Protein 170 
CAP-Gly domain-containing linker protein 1 (1427 aa, ~161 kDa) is encoded by the human CLIP1 gene. This protein plays a role in both centrosome… Expand
National Institutes of Health

Related topics

Related topics

12 relations
CLIP1 geneCLIP1 wt AlleleCell MovementCytokinesis
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Papers overview

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Highly Cited
2010
Highly Cited
2010
AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation
AMP-activated protein kinase (AMPK) is an energy-sensing Ser/Thr protein kinase originally shown to be regulated by AMP. AMPK is… Expand
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Highly Cited
2010
Highly Cited
2010
Phosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore-microtubule attachments.
CLIP-170 is implicated in the formation of kinetochore-microtubule attachments through direct interaction with the dynein… Expand
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2010
2010
Molecular insights into mammalian end-binding protein heterodimerization.
Microtubule plus-end tracking proteins (+TIPs) are involved in many microtubule-based processes. End binding (EB) proteins… Expand
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Highly Cited
2007
Highly Cited
2007
Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.
Microtubule plus end binding proteins (+TIPs) localize to the dynamic plus ends of microtubules, where they stimulate microtubule… Expand
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2005
2005
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior.
CLIP-170 belongs to a group of proteins (+TIPs) with the enigmatic ability to dynamically track growing microtubule plus-ends… Expand
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Highly Cited
2004
Highly Cited
2004
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization
Cytoplasmic linker protein (CLIP)-170, CLIP-115, and the dynactin subunit p150(Glued) are structurally related proteins, which… Expand
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2003
2003
CLIP-170 interacts with dynactin complex and the APC-binding protein EB1 by different mechanisms.
CLIP-170 is a "cytoplasmic linker protein" implicated in endosome-microtubule interactions and in control of microtubule dynamics… Expand
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2002
2002
The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase.
CLIP-170/Restin belongs to a family of conserved microtubule (MT)-associated proteins, which are important for MT organization… Expand
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Highly Cited
1999
Highly Cited
1999
Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin.
Based on a homology search with endostatin, the C-terminus 185 aa of collagen XVIII, we report the cloning, expression, and… Expand
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Highly Cited
1994
Highly Cited
1994
Molecular characterization of two functional domains of CLIP-170 in vivo.
CLIP-170 is a microtubule-binding protein isolated from HeLa cells that is involved in the interaction of endosomes with… Expand
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