C9orf72 gene

Known as: Chromosome 9 Open Reading Frame 72 Gene, MGC23980, C9ORF72 
This gene may play a role in cell death.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The hexanucleotide repeat expansion (HRE) GGGGCC (G4C2) in C9orf72 is the most common cause of amyotrophic lateral sclerosis (ALS… (More)
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Highly Cited
2014
Highly Cited
2014
A hexanucleotide repeat expansion (HRE), (GGGGCC)n, in C9orf72 is the most common genetic cause of the neurodegenerative diseases… (More)
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Highly Cited
2013
Highly Cited
2013
Expansion of a GGGGCC hexanucleotide repeat upstream of the C9orf72 coding region is the most common cause of familial… (More)
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Highly Cited
2013
Highly Cited
2013
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are devastating neurodegenerative disorders with clinical… (More)
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Highly Cited
2013
Highly Cited
2013
A hexanucleotide GGGGCC repeat expansion in the noncoding region of the C9ORF72 gene is the most common genetic abnormality in… (More)
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Highly Cited
2013
Highly Cited
2013
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative condition characterized by loss of motor neurons in the brain… (More)
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Highly Cited
2013
Highly Cited
2013
The finding that a GGGGCC (G4C2) hexanucleotide repeat expansion in the chromosome 9 ORF 72 (C9ORF72) gene is a common cause of… (More)
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Highly Cited
2012
Highly Cited
2012
A major recent discovery was the identification of an expansion of a non-coding GGGGCC hexanucleotide repeat in the C9ORF72 gene… (More)
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Highly Cited
2011
Highly Cited
2011
Several families have been reported with autosomal-dominant frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS… (More)
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Highly Cited
2011
Highly Cited
2011
The chromosome 9p21 amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) locus contains one of the last major… (More)
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